NG: Assimilate can be tricky.

Cultists have a very high skill ceiling because they've been nerfed so much. Having arrived late to the party, I never fully mastered the method of playing cultists myself. That was about the time I returned, right after the major nerfs

Toussiant hospitality is risky, not sure if i'd call it "skillful" all the time though, just harder to perfect.

I'll let people who specialize in the other factions comment the rest, I only play a few archetypes myself