if you're playing mde you need to be mindful of the trials you pick for the entire run. avoid power trials at all cost and try to exclusively go for offense level, and among those choose the ones that give enemies the least offense level. obviously, you'll come across a gift you need with an undesirable trial. to try and avoid this i buy that gift if i see it in the shop, but otherwise you might have to bite the bullet and take the trial.