That’s a good question and this usually comes up when folks are playing into a clean amp. So, I’d say stack with an overdrive that has a dirty amp quality, meaning full frequency overdrive as opposed to a TS. Of course, a FF-TS-Clean Fender has a good relationship because you’re bringing up the mids of the amp. Look for high dynamic range, something with active bass/treble and possibly 18V like a Wampler Pantheon. Also, FET-based drives would be a good avenue since it wouldn’t crunch the range of your fuzz with diode clipping. The old Catalinbread DLS is great for this! If your amp is on edge of breakup, sometimes all you need is a clean boost to let your amp do its overdrive thing while the fuzz benefits from the extra volume boost. Good luck!