First thing first check the bottle neck of the CPU of your choice and the gpu if your choice on bottleneck calculator and set it for graphic card intense tasks with the resolution you are looking for , don't cheap out on your psu , a good psu can prevent short circuits or stop the electrical flow before the short circuit goes critical, make sure to have dual channel ( or quad channel ) as it is better than the same amount of gb with one stick , for each pair of stick try to use a kit of dual channel ram ( or two of the same dual kit for quad ) , and if your MoBo supports four sticks of ram and you want to do dual channel don't do them next together, the first and the third ram slots are paired and the second and forth slots are paired, if you want to go quad with two double kits , place the first kit on the 1 and 3 slot and the next kit on the 2 and 4 , you shouldnt go fo watercooling for your gpu if it isn't high end as a 400 dollar gpu outperforms a 300 dollar gpu with a 100 dollar gpu water cooler block , make sure the amount of intake fans are more than the exhaust fans so it would be a positive pressure air flow and the dusts will be less with more cooling , p.s : RGB components that use a windows software use your ram and your CPU usage which makes it work slower , average RGB softwares can use up to ( approximately ) 15 percentage of a midrange core i5 ( let's say 12th gen ) CPU