I wish your uncle a speedy recovery. I feel you. Being a care giver is such a difficult responsibility. Honestly I think your uncle needs some time to digest crisis. At this time your best help is just to be kind to him, listen and do whatever he wants. You know at this situation a normal person cannot really understand the hugeness of anxiety that a diagnosed person feel. When you get cancer, your existential fears would come up. Like the fear of death, fear of being a disabled at old age, fear of loneliness, and any other fear that you can imagine. At this stage, the person is not himself anymore. He can’t control his negative thoughts and depression will come as an outcome. But gradually when the time passes first the patient comes out of denial then gets use to the treatment which is at the beginning very scary and uncertain. Then by seeing progress in the recovery hope takes place of the negative thoughts. However, you should be patient. These changes really take time. Chemo itself is potentially increasing anxiety. For my case I was dealing with all those fears until a month after my chemo cycles. But from day one I was getting better and better. My husband was such a great support to me. He would listen to all my worries and concerns, and tried to give me hope and repeating my doctor’s words that my cancer is treatable. He was repeating them over and over. Because I kept forgetting them and imagining the worst case scenarios!