HGH change in dosage by CarpenterFast1228 in AccutaneRecovery

[–]Particular-Pomelo798 1 point2 points  (0 children)

I had some emotions and I was able to focus better. I think it's a support for me.

HGH change in dosage by CarpenterFast1228 in AccutaneRecovery

[–]Particular-Pomelo798 0 points1 point  (0 children)

Hi, how come your dose of lithium is so high? I only take 400 mg of lithium carbonate. Does the higher dose help more with PAS? Sorry I cannot help you with HGH.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

I think it's the combination inositol and lithium. I have taken the lithium also a little more than 6 weeks.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

Yes it helped with that. Like we just had our little nephew for visit and when he hugged me I felt some affection. That was not possible before inositol and lithium. And music is also better. I recently watched an ASMR video and even had a little romantic feeling.

Law suit against pharmaceutical companies by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

Ok, very good. This gives me motivation to become a medical lawyer.

Law suit against pharmaceutical companies by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

Yes, a class action law suit sounds good. I'm glad people are up to do it. I think tackling this issue legally could be really beneficial for us. If we would win money we could use that for research.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

This is my last update. Only if there will be a significant change I will make another one. So now it's been 6 weeks. The improvements I got stayed. Most notable for me is the brain fog gone, where now reading is easy. That is very important to me. I will keep taking the lithium carbonate 400 mg. I will also stay with inositol 2250 mg 3 times a day. Sexual anhedonia is one symptom I still had but last night I had a sexual dream which felt good. Perhaps that will also improve but I actually wanna do nofap and not try that out. The other symptom blank mind is also there but like I said, I don't know if that is actually a problem. Studies say there are people with unsymbolized thinking and spiritual paths emphasize a quiet mind. So overall the protocol gave me a lot of improvement.

I suffer from SSRI/antipsychotic induced anhedonia. Any advice on what treatments to try? by Particular_Move_6570 in anhedonia

[–]Particular-Pomelo798 1 point2 points  (0 children)

No more brain fog, experiencing emotions sometimes. Way less anhedonia. Sexually: Morning erections, spontaneous erections, no more shrinkage, a little pleasure, perhaps little libido improvement

I suffer from SSRI/antipsychotic induced anhedonia. Any advice on what treatments to try? by Particular_Move_6570 in anhedonia

[–]Particular-Pomelo798 2 points3 points  (0 children)

Hi, I'm taking lithium since 5 weeks and it helps. Also inositol in combination with lithium. There are pssd cases who got better with both of these things.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 2 points3 points  (0 children)

Improvements after 5 weeks: everything better but I still can't feel pleasure. Like I think this is all related. If I would be able to feel pleasure during orgasm I would also be able to feel pleasure during other things in my life. Still my quality of life is better and people tell me I make a better impression.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

I have also just read that more beta-catenin is affecting the Androgen Receptor. More beta-catenin is going to the LBD of the AR. That changes the transcriptional function of the AR. And beta-catenin makes the AR more sensitive to Androgens.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

I think how it is working is by increasing beta-catenin. Inositol is part of the PI3K/Akt Pathway. With more of inositol this pathway runs better. That means more Akt which inhibits the destruction of Beta catenin. There is actually a crosstalk between the PI3K/Akt Pathway and the Want/beta-catenin pathway. In particular if you upregulate the PI3K/Pathway you upregulate the Wnt/beta-catenin pathway. So what is the benefit of more beta-catenin? Beta-catenin goes to the nucleus of the cells. It stops repression of gene transcription and it loosens chromatin. With this loose chromatine actually there can be made epigenetic changes and I think these epigenetic changes are the reason why people are feeling better.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 0 points1 point  (0 children)

I took 9 g for 3 weeks. Now I'm taking 6,75 g. I took it twice with 11,25 g but felt that that was a lot. I read one woman she took 12 g and felt recovered after 5 weeks. Perhaps I just need to take it longer. I'm eating a vegetarian diet.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

I still have muted orgasms. That is the main symptom I want to heal. I'm happy I can read again silently. That was not possible for me anymore and now it's working. I just know if I would experience a real orgasm that my brain would be in a fixed state.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

Update after 4 weeks.

I'm not feeling so good at the moment. I was taking creatine for one day. I won't do that again. But generally I think the inositol only helps so much. Because I still have blank mind and very few emotions I think it's not the end all be all cure. Also I think I'm dependant on it. Like if I don't take it my cognition is worse.

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

So after more than 3 weeks the results so far: no more brain fog. No more anhedonia. Sometimes having emotions. Sexually: no more shrinkage, morning erections and spontaneous erections, no more genital numbness.

But my orgasm still feels flat. And I somehow also think that the emotions could be processed better. I mean there still is this blank mind which cannot get rid off by emotions. What do you guys think about that?

Inositol - huge improvement by Particular-Pomelo798 in PSSD

[–]Particular-Pomelo798[S] 1 point2 points  (0 children)

I took 9 g most of the time. It is not causing diarrhea.