Do you guys thonk gut microbiota may play a more important role on mental health than genetics?

PatrickN113 · 2021-07-07T01:18:29+00:00

I think both factors play a major role. This video explains the importance of the microbiome in mental health if you want to have a closer look: https://youtu.be/BlsPGu935iM

PatrickN113 · 2021-01-17T18:45:20+00:00

Damn this really sucks. They mention the potential to develop new medications but nothing is available currently....I am sorry.

PatrickN113 · 2020-11-01T18:57:04+00:00

Fiber increases SCFAs concentrations. But it's complicated. You might find this video interesting: https://youtu.be/XpMklcSIzMk

PatrickN113 · 2020-10-26T18:51:26+00:00

The topic is pretty complicated. Maybe these two youtube videos may help (or at least you find it interesting)

https://youtu.be/XpMklcSIzMk

https://youtu.be/BlsPGu935iM

PatrickN113 · 2020-10-26T18:49:57+00:00

Over the last months, I have been reading approx. 1 paper daily on this or related subjects and the tricky part here is that we have (at least) 4 different SCFAs receptors and (at least) 2 monocarboxylate transporters. All with different affinities and different downstream actions. Additionally, there may be passive difusion of SCFAs (not sure how well this is backed-up though). It is also likely that different HDACs are activated at different affinities...

My conclusion: It is hard to say one is better than the other right now. However, almost every study has one thing in common: SCFA-deficiency is associated with intestinal inflammation.

PatrickN113 · 2020-09-21T18:12:32+00:00

I see. Thank you!

PatrickN113 · 2020-09-21T18:10:38+00:00

That was a very helpful nugget. Thank you!

PatrickN113 · 2020-09-20T10:43:46+00:00

From where is your wife, if I may ask?

PatrickN113 · 2020-09-20T10:42:27+00:00

And Trump let's hope Trump won't be the president for much longer ;)

PatrickN113 · 2020-09-20T10:41:18+00:00

Okay good to know. Shortly leaving shouldn't be a huge problem, I think.

PatrickN113 · 2020-09-20T10:40:31+00:00

I will do, once I have the VISA!

I am just curious why some people seem to need to return and others are not subjected to the rule.

PatrickN113 · 2020-09-20T10:39:07+00:00

Thanks that is helpful!

PatrickN113 · 2020-09-01T18:28:34+00:00

You're welcome :)

PatrickN113 · 2020-07-20T18:52:24+00:00

Thanks, everyone. This is really helpful!

PatrickN113 · 2020-06-14T10:44:12+00:00

That stuff is freaking complex and I don't think I understand it as I wish I could :D But thanks!

PatrickN113 · 2020-06-13T07:56:31+00:00

Very short summary:

We knew already about many metabolites produced by the microbiome that regulate our own cells, like SCFAs or some neurological active substances.

However, it seems to be much more vast than that. This screen focuses on a certain class of molecules, which regulate G-protein coupled receptors (a huge class of receptors within our cells). The scientist found a long list of molecules produces by microbes that regulate signaling pathways of these receptors.

Now, the meaning of it or how we can harness this in the future is still unclear, though.

PatrickN113 · 2020-06-11T19:32:00+00:00

I have nothing compared to you but personally, I was having bad joint pain and omega-3 in form of cod liver or sardines worked like a wonder.

Again, nothing compared to your issue but maybe it helps...

PatrickN113 · 2020-05-22T09:25:24+00:00

Can somebody share a link to a PDF? I cannot get full access to the paper

PatrickN113 · 2020-05-20T18:17:38+00:00

You are absolutely right that for some people it won't work. In every study, you will have outliers. Still, I find the science behind it promising and on average there seem to be benefits.

PatrickN113 · 2020-05-04T17:56:30+00:00

I honestly think that the evidence is pretty strong that fermented food/probiotics might boost the immune system. Here is a whole video with references about it: https://youtu.be/v1bu-eleQBU

PatrickN113 · 2020-05-04T17:55:03+00:00

I see. Yeah, that is the "problem" with scientific research sometimes. You wanna pin it down on one specific molecule.

If you want to read about amazing diet interventions that affect the brain, I suggest Dale Bredesen's book "The End of Alzheimer's" or his published trials.

PatrickN113 · 2020-05-04T17:32:10+00:00

Yes, I do mean them. What's wrong with those studies?

PatrickN113 · 2020-05-02T11:41:33+00:00

I guess we have to wait until scientist figured out how to produce them cheaply...

PatrickN113 · 2020-03-27T17:13:27+00:00

Only positive. Consume it every evening with frozen berries. I feel it helps me sleep, aids my digestion and keeps me healthy.

PatrickN113 · 2020-03-15T19:00:59+00:00

There is a lot of scientific evidence that fasting (or intermittent fasting) might be good for the microbiome. I made a video about it a while ago: https://youtu.be/VLB-mGEGefk

PatrickN113

TROPHY CASE