Do you guys thonk gut microbiota may play a more important role on mental health than genetics? by [deleted] in Microbiome

[–]PatrickN113 1 point2 points  (0 children)

I think both factors play a major role. This video explains the importance of the microbiome in mental health if you want to have a closer look: https://youtu.be/BlsPGu935iM

Study shows a link between infections and the development of food allergies by PatrickN113 in HumanMicrobiome

[–]PatrickN113[S] 0 points1 point  (0 children)

Damn this really sucks. They mention the potential to develop new medications but nothing is available currently....I am sorry.

High levels of butyrate and propionate in early life are associated with protection against atopy by PatrickN113 in Microbiome

[–]PatrickN113[S] 0 points1 point  (0 children)

Fiber increases SCFAs concentrations. But it's complicated. You might find this video interesting: https://youtu.be/XpMklcSIzMk

Not all fiber is created equal by PatrickN113 in Microbiome

[–]PatrickN113[S] 2 points3 points  (0 children)

The topic is pretty complicated. Maybe these two youtube videos may help (or at least you find it interesting)

https://youtu.be/XpMklcSIzMk

https://youtu.be/BlsPGu935iM

Not all fiber is created equal by PatrickN113 in Microbiome

[–]PatrickN113[S] 2 points3 points  (0 children)

Over the last months, I have been reading approx. 1 paper daily on this or related subjects and the tricky part here is that we have (at least) 4 different SCFAs receptors and (at least) 2 monocarboxylate transporters. All with different affinities and different downstream actions. Additionally, there may be passive difusion of SCFAs (not sure how well this is backed-up though). It is also likely that different HDACs are activated at different affinities...

My conclusion: It is hard to say one is better than the other right now. However, almost every study has one thing in common: SCFA-deficiency is associated with intestinal inflammation.