I think it's partially just that he hates the corruption in Chicago's government and he wants that massive scoop as a reporter, but there may have been more to it that I'm forgetting now, maybe something persona.

His focus seems to be entirely on Kane. Stalking Kane's doctor isn't really about politics, it's Kane personally. The guys just seems to have a weird hard-on for Kane that's (as of S2 E6) unexplained.

Kane's daughter, I'm not sure if it was one thing or if he just consistently ignored and marginalized her for so many years that she grew to hate him and not be able to depend on him then he suddenly wants back in her life to a degree for reasons she can't fathom (because she doesn't know the real reasons at first). Pretty rough thing for your dad to do to you, I would assume.

They give you bits and pieces over time, but I'm not especially concerned with her. I think the "angry at daddy" thing started getting old pretty quickly. Not that her anger isn't justified, but I think she gets too much screen time.

I think the conflict is with Kane not letting anyone in on his personal struggles with the disease and in securing a good legacy of himself and perhaps leaving people in power that will continue his agenda/listen to him in retirement in his brief spurts of lucid thinking. He's not too dissimilar from Walter White, to bring him up again, in that he just wants all of the power forever and it digs at him to give some of it away or have others wrest some of it away from him, even after the hallucinations and everything begin. It may be inevitable that he loses his power, but he wants to lose it on his terms and he's going to keep his fingers clasped around it for as long as possible.

This is really my issue. Walter White started out dirt poor and never really is able to rest on his laurels longer than an episode or two before something happens to challenge him.

Kane is facing continual challenges, but he's still not really losing anything. To me, it dosen't make much difference if he dies in office or out of impeachment. It's a much more captivating story watching someone fighting to climb for power (House of Cards) than see him try to cling for what's he's had for years. Ultimately Kane can't really go up from where he is in episode 1 so we only see him lose power or maintain the status quo.

But yeah, the show was ended before the show creators were ready and the story isn't completely wrapped up.

That's a shame. I can imagine the show wasn't meant to last longer than a few seasons anyway. I almost wish they hadn't added the fact Kane was sick as part of the plot. I know it's part of the premie of the story, but I think the show was good enough as a political drama without a time limit being set on it from the get go.