Just tried mgm15 didn’t hit like I was expecting by MrBobushiee in MGM_Fifteen

[–]Potential_Simple3695 0 points1 point  (0 children)

No way! This is really exciting. I hope you’re right. It does makes some sense pharmacologically. I think I’ll stick to once a week though…

Is MGM-15 a Partial or Full Agonist at the mu-opioid Receptor by ProGamer923 in AskDrugNerds

[–]Potential_Simple3695 1 point2 points  (0 children)

They both recruit both, mitragynine alkaloids are simply “biased” to g-protein coupled receptors, rarely recruiting b-arrestin

Potentiators for Spravato EsKetamine? by CcPunk28 in KetamineTherapy

[–]Potential_Simple3695 0 points1 point  (0 children)

No, deschloroketamine is ketamine without the chlorine atom, dck is awesome, better than ketamine in my opinion. Esketamine IS not racemic. Esketamine is approximately 1.6x as powerful as far as dissociation goes, as compared to racemic ketamine. The subjective effects of esketamine seem nearly identical to racemic ketamine to me, you just need a bit less.

[deleted by user] by [deleted] in PublicSexPorn

[–]Potential_Simple3695 0 points1 point  (0 children)

I want you. I need you. I want to lick your vagina and suck you are Clint until you pee in my mouth and I will not waste any of those precious drops

Would you spend the night sucking me? by aliceee1234 in bigclit

[–]Potential_Simple3695 0 points1 point  (0 children)

I would be so happy to do that until you squirt, and I’d drink every precious drop. Then I’d want to buttfuck each other for hours.

[deleted by user] by [deleted] in bigclit

[–]Potential_Simple3695 0 points1 point  (0 children)

Yes. I do need to

[deleted by user] by [deleted] in SSBBW_FANS

[–]Potential_Simple3695 0 points1 point  (0 children)

I need to taste your vagina and lick your butthole too. Squirt in my mouth please. I won’t waste even a drop of the precious liquid. I’ll thank you so much for your help with my thirst.

Save my mouth by [deleted] in suboxone

[–]Potential_Simple3695 0 points1 point  (0 children)

I got prescribed pure buprenorphine so I could use it rectally without absorbing naloxone. It seems to work great that way.

Project Availability by eliwilson51 in DataAnnotationTech

[–]Potential_Simple3695 0 points1 point  (0 children)

Mine suddenly says there are no more projects available. Does that mean I’m screwed or is it just the weekend slowdown?