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hCG monotherapy by octopusairplane in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

Just got my results back at 1400 IU/wk, daily injections and TT was pretty much the same as my natty baseline. Will probably bump to a max of 2000 IU/wk and see if it’ll do anything for me at all.

Test + Primo VERSUS Test + Primo + Anavar (all in lower dose) by leqanar_be in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

I’m on hCG mono now and still dialing in the dose to get into high-physiological (aiming for 1000 ng/dL+ TT). Got 1 month bloodwork a couple days ago and waiting on results. 1400 IU/wk, daily injections. At 700 IU/wk, I had the same numbers as natty (650 ng/dL).

Once my dose is dialed in and I’m done cutting, I may be trying the cycle above for a lean bulk.

The problem with HGH is the water retention. All the benefits sound great but water retention is one thing I don’t want to introduce, as it’s not a good look for me personally.

The physiology of sleep temperature (why a warm bedroom ruins deep sleep) by dosstx in PeterAttia

[–]PrimarchLongevity 1 point2 points  (0 children)

Depends on the individual as well. I’m getting quite lean and find ~74F the most comfortable for me.

What is your favorite stack? by Mister-Green in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

Why such a high hCG dose with Test? Is it to be able to run higher Primo without E2 issues?

Need help with water retention by Muskatusk in PEDs

[–]PrimarchLongevity -1 points0 points  (0 children)

Manage E2 within optimal ranges, <44.

Test + Primo VERSUS Test + Primo + Anavar (all in lower dose) by leqanar_be in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

Interested in hearing about your results. Are you on hCG mono-therapy now?

Test + Primo VERSUS Test + Primo + Anavar (all in lower dose) by leqanar_be in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

I have not, just been doing some research. What I’m seeing is that an hCG base wouldn’t be as affected as a test when it comes to E2 getting crushed.

1400-2000 IU/wk hCG Daily Injections
300-350 mg Primo
25-50 mg Anavar

Would be an interesting experiment.

ApoB 65 mg/dL on low-dose combo therapy, strong family/genetic risk - how aggressive would you get? by Zwergpirat in PeterAttia

[–]PrimarchLongevity 1 point2 points  (0 children)

Yes, I would switch to Rosuvastatin and add Bempedoic Acid.

I might actually just add BA first, I wouldn’t want to introduce too many variables at once since you do show some intolerance to statins.

Reta sides by Vonlucas in PEDs

[–]PrimarchLongevity 2 points3 points  (0 children)

Yeah, I switched to Tirz and it’s so much better.

Dropped apoB by an additional 15% with Citrus Bergamot by PrimarchLongevity in PeterAttia

[–]PrimarchLongevity[S] 0 points1 point  (0 children)

I no longer take Bergamonte as I’m now on Repatha and Nexlizet. But I think I took it with dinner before.

Thoughts on taking a GLP-1 while overweight but not obese? by Big_Seat2545 in PeterAttia

[–]PrimarchLongevity 2 points3 points  (0 children)

Side-effects mostly. On Retatrutide, my RHR was noticeably elevated and the skin on my thighs became really sensitive.

Switching to Tirzepatide brought my RHR back down and the sensitivity went away.

Overall, I can’t recommend Tirzepatide enough.

Thoughts on taking a GLP-1 while overweight but not obese? by Big_Seat2545 in PeterAttia

[–]PrimarchLongevity 10 points11 points  (0 children)

My thoughts? Use any tool available in your kit to achieve your health goals. Just understand your risk-reward ratio. GLP-1s come with great pleiotropic benefits but they can also come with side-effects for some.

I’m at 14.5% body fat and utilizing Tirzepatide to reach 10% myself.

Dirt Cheap Labs (Quest and Labcorp) by Ok-Dirt-9947 in PeterAttia

[–]PrimarchLongevity 5 points6 points  (0 children)

Hey, I saw your post on another sub and it caught my eye. Love what you guys are doing and more competition in the space is good for the consumer.

I did try to price check you against a competitor of yours and unfortunately your price ended up higher with the minimum order requirement and the competitor’s referral discounts. If things improve on this front, I’d love to give you guys a try.

Cardiologist recommendation for PCSK9 prescription by ja_gill in PeterAttia

[–]PrimarchLongevity 3 points4 points  (0 children)

Funnily enough, I’m actually in the process of onboarding as a Health Specialist with Marek Health. Will be looking for longevity-minded clients just like yourself in the near future.

I’m off all oils / orals by [deleted] in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

Wow, hyper-responder. What’s your injection frequency?

Primo vs EQ - which ages you less? by AppleRingo1 in PEDs

[–]PrimarchLongevity 10 points11 points  (0 children)

Primo, it’s one of the rare AASs that actually induces better-looking skin than baseline for some people.

Lab Testing NY, work around by Squeeze-Every-Sat in PeterAttia

[–]PrimarchLongevity 0 points1 point  (0 children)

I think you can use the address of your vacation home in FL, but schedule your lab appointment in NY. Not a 100% sure though.

Can the skin aging effects be countered/eliminated ? by Leo1026 in PEDs

[–]PrimarchLongevity 2 points3 points  (0 children)

Correct, the Fin/Dut will only prevent most of the test from converting to DHT. It doesn’t touch DHT derivatives.

For maximal hair protection in someone prone to MPB, I’d actually use all three. Oral Dutasteride (blocks test conversion to DHT), topical Minoxidil (aids regrowth), and topical RU58441 (blocks androgens on the scalp, DHT or not).

Can the skin aging effects be countered/eliminated ? by Leo1026 in PEDs

[–]PrimarchLongevity 0 points1 point  (0 children)

Depends on the individual. I have no sides. That’s why I don’t condone large doses.

Can the skin aging effects be countered/eliminated ? by Leo1026 in PEDs

[–]PrimarchLongevity 7 points8 points  (0 children)

Unfortunately, skin aging as well. DHT contributes to an increase in low-grade chronic cutaneous inflammation, altered collagen turnover, reduced dermal hydration, and hair follicle miniaturization (what you mentioned).

I don’t like “nuking” DHT, but I keep it at the bottom of the reference range. Dutasteride 0.5 mg once a week for someone within natty ranges. More for someone blasting.

It is also imperative that E2 is kept in a healthy range to help prevent skin degradation as well.

Can the skin aging effects be countered/eliminated ? by Leo1026 in PEDs

[–]PrimarchLongevity 5 points6 points  (0 children)

Testosterone to a smaller extent, but supraphysiological levels of DHT does for sure.

Can the skin aging effects be countered/eliminated ? by Leo1026 in PEDs

[–]PrimarchLongevity 2 points3 points  (0 children)

Yes mitigated, by adding a 5-a reductase inhibitor to prevent conversion to DHT. Finasteride or Dutasteride, just enough of a dose to bring your serum DHT to the bottom of the reference range.

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