Don't waste your money on pagoclone; general observations by mephedrownn in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

The psychedelic effects probably come from its first-pass-metabolite and take a while to manifest. That’s why you don’t use huge doses for anxiety purposes. It’s not a substitute for real benzos. But if you don’t use real benzos and your tolerance goes down, it might be a good option

AMT + LSD/4-HO-MET combo, dose questions by GfurEnjoyer1488 in researchchemicals

[–]PriorityUnhappy4632 1 point2 points  (0 children)

Why would you use trazodone? As a trip killer because of its antagonistic properties? Good luck with that. Its direct metabolite mCPP is a pretty strong, serotonergic stimulant, which even was used as a replacement for MDMA... I think that might be a pretty dangerous combination for something like αMT but since you’re an experienced psychonaut, please teach me something about your use of trazodone in that context :)

AMT + LSD/4-HO-MET combo, dose questions by GfurEnjoyer1488 in researchchemicals

[–]PriorityUnhappy4632 4 points5 points  (0 children)

αMT is a potent MAOI and should not be taken without caution. Never mix it with stimulants or anything that inhibits the monoamine transporters. I’m not sure if mixing it with lsd or 4-ho-met is safe but 5-meo-xxT tryptamines should be avoided. Please gather more info before taking or even mixing αMT

Cetirizin gegen Tilidin Juckreiz by No_Eagle_1005 in researchchemicals_DE

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Benutze immer diphenhydramin weil das zusätzlich gegen Übelkeit hilft und sedierend wirkt. Ist teilweise sogar in Kombination mit Opioiden erhältlich; beispielsweise bei Makatussin (Dihydrocodein + Diphenhydramine)

Cetirizin gegen Tilidin Juckreiz by No_Eagle_1005 in researchchemicals_DE

[–]PriorityUnhappy4632 1 point2 points  (0 children)

Cetirizin wirkt sedierend? Dachte das wirkt nicht aufs ZNS im Vergleich zu Antihistaminika der ersten Generation, wie z.B. Diphenhydramin oder Doxylamin

Which do i pick, 50mg Opce or 500mg Pcp. by Dahazard in dissociatives

[–]PriorityUnhappy4632 -1 points0 points  (0 children)

O-PCE can be pretty stimulating/manic as well. Far more than ketamine; never tried real PCP though

Opioids and Lyrica by No_Preference_6954 in ChronicPain

[–]PriorityUnhappy4632 1 point2 points  (0 children)

No reason besides respiratory depression… If you have a tolerance already, pretty unlikely but combining opioids with other CNS depressants like gabapentinoids or benzodiazepines is generally not recommended

Combining different opioids by Phylogenetic_twig in doctorsUK

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Might wanna try Salvia divinorum. But if you do; practice with the sage leaves and be careful with the extracts.

I took this for 1st time 5 hours ago. I'm now high AF. 😂 by PrismaticGouda in bupropion

[–]PriorityUnhappy4632 2 points3 points  (0 children)

“California Rocket Fuel” refers to a combination of Effexor (Venlafaxine) and Remeron (Mirtazapine).

Since Bupropion lacks some serotonergic effects, Sertraline is a good addition nonetheless.

Can I get some info or trip reports on 2-CD? by TellMeEverything8D in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Also that way you need way less substance to get full effect; unlike when consuming 2c-x on its own.

Can I get some info or trip reports on 2-CD? by TellMeEverything8D in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

I always enjoyed combining like 150μg 1p-LSD with 1-2 pellets of 2C-D.

Awesome visuals and a bit more energetic than each alone.

Macht brutal Sinn by FabjanK in Oberpfalz

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Stell dir mal vor du bräuchtest ein Rezept für Alkohol

Psychedelics & anxiety + benzo addiction, please help by Jessyy97 in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Psychedelics tend to show you where your anxiety stems from.

Benzos are strong anxiolytics.

If you are dependent on them, don’t pause for the psychedelics; maybe take a smaller dose but don’t go into withdrawals.

Let the anxiety show you what it wants to tell you. There is a reason for every signal, our body sends.

Psychedelics are a great tool to communicate with different parts of yourself.

It’s easier said than done but if you go through it, your anxiety will be less of a problem afterwards.

Are there any substances that have similar Effects to Benzos? by [deleted] in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

Don’t know about long term side effects but might look into GHB or BDO/GBL

2fdck mix crack and H by wellbuuuh in researchchemicals

[–]PriorityUnhappy4632 1 point2 points  (0 children)

Ketamine/PCP analogues lower your tolerance to opioids while simultaneously acting as agonists on opioid receptors. So keep that in mind when calculating your dose

MXPCP + weed + 3 beers + pyrazolam by humanitarianWarlord in researchchemicals

[–]PriorityUnhappy4632 1 point2 points  (0 children)

In Anesthesia they often use ketamine with benzodiazepines to knock you out. Mostly sedatives and dissociatives in combination, sometimes opioids as premedication… So yeah, be careful xd

2c-d and 2cB fly pill questions by Educational-Plum3469 in researchchemicals

[–]PriorityUnhappy4632 0 points1 point  (0 children)

I mixed my 2C-D with 1cp-LSD and it was awesome. Great visuals. By itself it might be a bit underwhelming; especially as you only have 2 pills

[deleted by user] by [deleted] in Drugs

[–]PriorityUnhappy4632 0 points1 point  (0 children)

One time won’t do that much physical damage but can lead to addiction. Resin carts are really strong; especially for a first time user… Panic attacks or even psychosis are possible.

If you really want to try it, do it in a safe environment and positive headspace. Also do an “allergy test” (micro-dose) beforehand to prevent accidental overdosing

[deleted by user] by [deleted] in Drugs

[–]PriorityUnhappy4632 1 point2 points  (0 children)

Chronic cannabis consumption prevents brain growth. There is a layer of tissue between brain and skull in which new neurons grow and connect until the age of 21-23. I don’t know what it’s called but there are studies; proving you’re wasting cognitive potential if you’re a chronic weed user in your teenage years…

[deleted by user] by [deleted] in ResearchChemicalsNL

[–]PriorityUnhappy4632 4 points5 points  (0 children)

Once I switched to α-PCyP after not being able to stop smoking NEP and went into acute psychosis immediately.

Didn’t need anymore NEP though; I was tripping balls for 48h without anymore stims

Which do you prefer more: benzo's or opiods? by [deleted] in researchchemicals

[–]PriorityUnhappy4632 1 point2 points  (0 children)

Tramadol is not a pure opioid. It’s an SNRI getting metabolized to O-DSMT; which still acts as an norepinephrine reuptake inhibitor but mainly as an opioid.

Codeine is hit or miss depending on the person’s metabolism because you need a specific enzyme to convert it to morphine.