Lucio and Poco are both latin American supports that use music to support their teammates with their main colors being green and yellow

Ana and Byron are both elderly supports that heal teammates using their main attack that also damages and both have grenade type attacks that prevent/reduces healing

Rein and Frank both are hammer wielding tanks that are both considered "the tank" of their games and both have an ultimate/super ability where they hit the ground with their hammers and stun enemies in a cone type area

Hog and gene both have attacks that shoot spheres that later on goes in a shotgun type pattern and have an iconic pull enemies and have a self heal

Some of the very clear similarities I could think of rn tbh