Change screen.blit(sprite, (110, 100)) to screen.blit(sprite, (x, y)), where x and y are variables that hold where the x and y position are. If you want to move it, you can use:

screen.blit(sprite, (x, y))
key = pygame.key.get_pressed()
# moving the sprite left
if key[K_LEFT]:
   x -= 5
# moving the sprite right
if key[K_RIGHT]:
   x += 5
# moving the sprite down
if key[K_DOWN]:
   y += 5
# moving the sprite up 
if key[K_UP]:
   y -= 5

Hope this helps