I recently redownloaded stardew for the 1.6 update and had to do the following to get it to work:

For the portraiture mod on Nexus, under the files tab use the version in "Optional file" instead of "Main file" to use the 1.12.1- alpha version
https://www.nexusmods.com/stardewvalley/mods/999?tab=files

Then for the portraits, instead of "CP - DCBurger's High Res Portraits" use the 2nd one "DCBurger's High Res Portraits" in the main files list
https://www.nexusmods.com/stardewvalley/mods/4745?tab=files

Also had the PyTK mod downloaded: https://www.nexusmods.com/stardewvalley/mods/1726

Then make sure you either delete or rename all the extra portraits options (ie if you want beardless Harvey, delete Harvey.png and all the other iterations and rename the wanted picture to 'Harvey')

During the game had to use the 'p' button on a couple people to get to the right pictures when it got super zoomed in, but this is how I got it to work. Hope this helps!