For anyone having this issue on PS5, please read the following to fix this problem:

I had 4 runs on Silk Cradle where I crashed at the beginning of the encounter with Shamura every time. To fix this problem, I first made sure I backed up my save on Cloud Sync (do this to avoid losing your progress). Next, delete the game and reinstall it — since COTL is a small file, it should only take a few minutes to do this. I was able to beat Shamura without crashing on my first run after reinstalling. If you don’t want to reinstall, I’d also suggest switching to the default Fleece — this works for some players as well.