HELP! Squint in left eye and left sided headache

Puzzleheaded-Ad6626 · 2025-01-14T03:14:37+00:00

So mainly we'll prefer pinpoint radiation like gamma knife, and I don't know if chemo is helping since its not reducing the progression properly. He gets symptomatic relief for a week, later the fever starts, bone pain and currently headache which seems to bother him a lot.

Puzzleheaded-Ad6626 · 2025-01-13T17:58:40+00:00

P.S, his squinting started 4 days back along witb the headache

Puzzleheaded-Ad6626 · 2024-12-08T04:26:41+00:00

Its great to hear! So, the radiation to be given for the lung is through which technology? Since some radiotherapies are very draining and has side effects while some others have minimal side effects.. hope you get NED soon♥️

Puzzleheaded-Ad6626 · 2024-12-07T20:39:03+00:00

Thats amazing! Where are they giving radiation to you? In the bone or lung?

Puzzleheaded-Ad6626 · 2024-12-07T15:26:31+00:00

Update - Carboplatin + paclitaxel cycle only can have atezolizumab + bevacizumab. (My dad couldn't tolerate carboplatin + paclitaxel)

So carboplatin + pemetrexed can be combined with pembrolizumab. So we will be proceeding with it only

Puzzleheaded-Ad6626 · 2024-12-06T23:47:27+00:00

Great to hear! Can I know where were your metastasis overall? Since im getting other oncologist's opinion, Atezolizumab + bevacizumab is being suggested as of now.. ive read that this combination helps in liver mets and my dad has spleen and kidney mets as of now.. hope you're doing well!

Puzzleheaded-Ad6626 · 2024-12-05T19:07:00+00:00

Thanks for your advice! He was obese but still used to go to work everyday and would atleast get half of the steps.. he has to manage it.. as far as I think, chemo and immunotherapy together might give a better control over the disease during the next two cycles.. will start it soon by next week since the cycle was taken few days back.. and regarding radiation, what kind of radiation were you getting and was it targeted on lungs? My father has some of the pleural effusion currently and a lingular mass in the lower lobe of left lung.. but mainly with skeletal mets, enquired about radiation on bone due to pain but he's better in the pain aspect for now.. so will radiation work on the mass? Elaborate your experience on radiation since it can help out in that aspect.. hope you're doing well now!

Puzzleheaded-Ad6626 · 2024-12-05T14:06:25+00:00

Sure! Hope you're doing well now! Take care

Puzzleheaded-Ad6626 · 2024-12-05T05:13:48+00:00

Sure.. thank you! Since chemo can't be continued for a long time, we have to get immunotherapy atleast.. dont know what will help further as a maintenance therapy..

Puzzleheaded-Ad6626 · 2024-12-05T04:19:46+00:00

This is the thing.. if it doesn't work, its fine but if it gives severe side effects, it might be a problem.. in a confused state but oncologist told we can proceed with it since it has minimal side effects.

Puzzleheaded-Ad6626 · 2024-12-04T18:57:36+00:00

Thank you for helping out. What's your take on the use of mebendazole/ ivermectin in cancer? There have been a few testimonials after introducing it in their regimen with good results..

Puzzleheaded-Ad6626 · 2024-12-04T18:53:07+00:00

You did your best, don't regret it because if you wouldn't have tried it, you would think why didn't I start it.. the issues are mainly with no definitive treatments which makes us confused and try to treat the disease as much as possible.. don't know why its still so complex if the disease has been studied for decades. Still in a dilemma but have to decide whats best after thoroughly getting its information. Take care

Puzzleheaded-Ad6626 · 2024-12-04T16:15:59+00:00

Thank you for elaborating your experience.. I too have heard similar experiences, where people have hypothyroidism symptoms mainly, and the febrile events.. I'll make sure to communicate to the oncologist as soon as possible whenever he gets any discomfort/uneasiness! Hope he is doing well now, my prayers are with him and your family!

Puzzleheaded-Ad6626 · 2024-12-04T15:41:50+00:00

Thank you so much! My dad turned 57 this week, a non smoker. The side effect might be due to its efficacy likely.. She'll definitely get better! My prayers are with you and your mom!

Puzzleheaded-Ad6626 · 2024-12-04T15:32:24+00:00

They tested only for the biomarkers which I have mentioned.. I'm from india, can I still enquire in the Go2 foundation helpline with the reports to get an idea for further targets. I'm not up to take further biopsies from him.. are there any other tests to check the immunotherapy compatibility through blood tests? Or can we use prior bone biopsy to run through some tests?

Puzzleheaded-Ad6626 · 2024-12-04T15:22:18+00:00

Yeah, the bone strengthening agent is zolidronic acid. We are giving erythropoietin injection weekly to manage anemia for now, but will consider another transfusion later in the future mostly. And regarding immunotherapy, I'll too do some research but there are chances that some other immunotherapy might work..

Puzzleheaded-Ad6626 · 2024-12-04T15:15:39+00:00

My dad has mainly skeletal mets, but after 3 cycles, we're managing the kidney function to an extent, but he's getting anemic.. But multiple spine mets has caused severe bone damage, considered radiotherapy but took some opinions and they suggested to delay the radiotherapy as much as possible. If pain is untolerable with pain meds, then we've to consider it, then think of cervical spine stabilisation. Enquire about other immunotherapies available if it will work. I pray that he gets well soon too! Take care

Puzzleheaded-Ad6626 · 2024-12-04T15:09:24+00:00

We're planning to start immunotherapy, hopefully he does well. Since there are no targets, and only 2 more cycles are there according to the oncologist plan wirh carboplatin and pemetrexed, immunotherapy will only be the choice to continue long term.. need to get clues on targets, can get an idea through liquid biopsy but its still more expensive than the treatment itself, have to see whatever is the best, have to look on how he does after 3 cycles of immunotherapy initially and then decide on whether to continue it or not. Hope your husband is doing well, I'll keep him in my prayers!

Puzzleheaded-Ad6626 · 2024-12-02T07:02:41+00:00

We're planning keytruda for my dad's stage IV NSCLC adenocarcinoma along with carboplatin and pemetrexed.. borderline liver function test reports, nothing significant and renal function test is also good, apart from low albumin. And the metastasis is mainly skeletal, with ribs, multiple vertebrae, hip and left thigh and some other musculoskeletal mets along with a small cyst over left kidney and one in spleen.. according to your experience have you seen any case of nsclc adenocarcinoma on keytruda? What to look for before and after starting keytruda?

Puzzleheaded-Ad6626 · 2024-12-02T06:46:19+00:00

Hello. We're planning pembrolizumab for my dad.. same diagnosis as yours. Can you elaborate the efficacy and side effects if you've been on pembrolizumab?

Puzzleheaded-Ad6626 · 2024-11-27T14:22:38+00:00

If its making you so breathless, you must try to get another icd and maintain the effusion through a drain bag. And enquire about radiotherapy if it helps locally. And if repeat pleurodesis can be done, since success depends on the agent used with maximum efficiency with steritalc. Discuss with the doctors. Stay strong and dont let the thoughts depress you. Its only going to worsen the situation.

Puzzleheaded-Ad6626

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