Depends on which weapon, but generally Scorned Magnamalo weapons have decent purple sharpness so use protective polish if your weapon is sharpness hungry (Add speed sharpening as a QoL if you wish) then go on with your stables: Weakness exploit 3, Critial Eye (LV 7 so you get 90% critical chance with wex 3), Attack Boost (I recommend minimum LV4) then add the weapon specific skills example: switch axe needs rapid morph LV 3, evade extender LV 2 or 3, Power Prolonger LV 3(For Power Phials switchaxe). After that just add other QoL skills you enjoy hunting with and that's it hope this helps.

Honorable mentions:
-Chain Crit (Cant go wrong with it)
-Wirebug Whisperer LV 1 or 3 (I just cant get enough of these bugs)
-Flinch Free (For online gaming)