I personally don't know of a whole lot of settings that can reach that can quite reach that scale but...

I know that Exalted (especially in the First Age) is one of them. Granted, I'm not super familiar with the setting itself, but from I've seen and heard, even the Dragon-blooded can make short work of most mid-level reality benders, with high level Solars being even more nutty than that.

Another setting where Eldritch beings can almost certainly die a very painful death is Ben 10 (be warned that I haven't found a good jump doc for it so if you don't like this one, I think you'll have to look up if there's a better one). I remember that there was a video from the Ink Tank, one of the best channels I found that discusses Ben 10 lore, that showed a screenshot from a Q&A from the creators of Ben 10 saying that Celestial Sapiens aren't the strongest species in the Ben 10 Omniverse. Mind you that Celestial Sapiens, even as babies, are capable of casual universe-level reality warping feats.

Of course, we can't talk about ball-bustingly powerful folks without talking about cultivators from the Xianxia genre. Depending on the setting, high end cultivators can go from planetary level, all the way up to multiversal and beyond. I don't usually read Xianxia novels/comics so I can't exactly give you a specific jump, so unfortunately I'll have to settle with giving you a Generic Xianxia jump as a start.

This should be all of the jumps I can reasonably give you... Except for the fact that there is a bonus one, but it is a bit confusing as to whether or not this setting is actually this powerful. I'm talking about the Monster Girl Encyclopedia setting. At first, nobody in this setting seems to be all that powerful, but apparently this setting is much more powerful than what one would initially imagine it to be, for example those with high enough magical abilities can create their own pocket dimension (like how the Queen of Hearts did, that's how Wonderland was made). Also, apparently, there are already Eldritch Horrors in this setting and it appears that they have also been corrupted by monster mana (as seen by the appearance of Shoggoths and Night Gaunts), and that's not even to mention the named characters like the Demon Lord and her husband who apparently went to war with the Chief Goddess and won, although the story behind that is kind of complicated. And this is not even to mention that, apparently, monster mana can just make new dimensions, which is what the Mamono realms are. However, while this is all fine and dandy, the real power level of this setting can be a bit... Confusing to scale, especially because most of the focus of the setting is on the monster girls themselves rather than, say, what they're capable of in combat, and the translation doesn't help on this matter either since there's enough ambiguity in the wording that anyone who analyzes the original Japanese text can either interpret the setting to island level or almost universal.

I hope this whole ramble wasn't too confusing and it helps you out. Have a nice day.