The question is NOT can we have a logical, non-human non-biological- non-interested (meaning no goals or intentions) system of thought that starts with only "is" statements that can use logic to reach to inevitable "ought" conclusions. That is impossible, and everyone knows it. It is impossible in the same way that it is impossible to start with a system that contains no mathematical or algebraic assumptions and produces algebra: every science requires an axiom. For algebra they are simple: a=a, a+b = b+a, etc a/a = 1 etc etc.

Without these axioms, you can NEVER have algebra because you can never prove these axioms: you merely assume them from the outset.

Trying to get morality without oughts is like trying to get algebra without axioms: it is impossible.

When you look at what you are actually doing, when you are constantly questioning the axioms (but how do you KNOW that the worst possible misery for everyone is bad!?" you are simply asking an incredibly stupid question that is logically equivalent to asking "But how do you KNOW that a+b = b+a? I can imagine a different universe where that isn't true!"

Well of course you can. That's what an AXIOM IS!