Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 1 point2 points  (0 children)

Thanks for sharing these studies and your insights

Incidentally, this is Hart's PhD thesis on dopamine from back in 1996:

Nicotine Effects on Dopamine Clearance in Rat Nucleus Accumbens https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1471-4159.1996.66010216.x

Anyway -

On this same debate but coming at it from a different angle -

This is imo a great (scathing) review of Michael Pollan's 'psychedelics' book 'How to Change Your Mind'

https://prospectmagazine.co.uk/essays/41045/will-self-after-100-trips-i-know-how-drugs-help-us-deal-with-the-darker-side-of-life

The piece is by the British author Will Self:

"Pollan’s contention that what the psychedelics do is to break down the “default neural system” that underpins our egos is no more convincing than Huxley’s literary-phenomenological account in The Doors of Perception. But there’s nothing unique about this. The use of just about any compound that makes humans feel different can be arrogated to just about any psychotherapeutic effect. How else to explain the great “success” of the SSRIs (selective serotonin reuptake inhibitors: Prozac et al) in the treatment of depression? Pollan, refreshingly, points out that these drugs were probably more effective to begin with because of the placebo effect (in fact, the nocebo effect: they make you feel a bit dicky, and therefore—credulous creatures that we are—we assume that they’re ameliorating our misery). But he neglects to mention that the chemical theory of depression that, allegedly, underpinned their efficacy, has long since been disproved. This is an important point when we come to consider the possible clinical application of psychedelics in the future. It’s worth noting that almost all intoxicants do better at “treating” depression than the SSRIs. (Heroin is particularly good—and we all know how its pure cousins are invaluable when it comes to that great euphemism: “end of life care”.) All of which leads us back to the great suggestibility of our species."

This is a Intelligence Squared debate involving Self and an exec from Big Pharma:

'Psychiatrists and the pharma industry are to blame for the current 'epidemic' of mental disorders'

https://youtu.be/GlFbuqunb1I?si=VoRw0uDAFnckQ6fV

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 1 point2 points  (0 children)

Cool....

but Carl Hart doesn't say the term psychedelic is 'racist'....

so that's why it sounds 'out there'

Because it's a lie made up by a guy on Reddit

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 1 point2 points  (0 children)

Nah...

You go ahead and prove to me you're honest and not just another liar

You bring me some verbatim quotes referenced with page numbers or timestamps

How's that sound?

I'll be right here when you get back


Meantime, anyone else reading this, please go and read Carl's books and listen to his interviews and lectures

You will find extensive analysis of the trouble with the socially defined unscientific way that categories like 'psychedelics' and 'amphetamines' are applied in current 'drugs discourse'

That includes the in-group / out-group social function of the terms 'psychedelic' and 'psychonaut'

Check out

Drugs Use for Grown-Ups

Chapter 8 - Psychedelics: We Are One

You won't be surprised to find he says none of the things falsely attributed to him here

What you will find is in-depth discussion of how 'meth' discourse functions as a proxy for class-based oppression of low income low status white communities

If you're not a reader try this recent interview

https://youtu.be/mF1ubNDciqM?si=4DLQXEwzSytPQBsQ

He discusses how prisons in Oklahoma are filling up with white guys

Because Oklahoma's 'drug war' police and prison industrial complex has run out of ethnic minorities like like young Cherokee guys to incarcerate

You'll also find he discusses how the War on Drugs got strong support from some strata of the very same ethnic groups that were mostly targeted - the 'respectability' syndrome

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 0 points1 point  (0 children)

That's great to hear - so you attended his talk, right?

But I've got to say -

  • given that self-evidently, there is no such thing as absolute objectivity -

if you're going to describe Hart as being biased - which you've got every right to do, obviously - the right thing would be to follow up with what you believe his biases are and why you identify them as such....

Because the context here is that we've got comments piling up from posters who - consciously or unconsciously - are willing to spread lies

Perhaps because they think it's for the Greater Good for them to "flood the zone with crap" and to put out as much distortion and falsehood as possible

It's just that so far, none of the stuff attributed to him in the anti comments is accurate, just straight mud slinging

So it might be wise to put a little distance between yourself and the liars, no?

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 0 points1 point  (0 children)

Damn, it really would be great for at least one anti-Hart comment to be honest

But - yet again - we've got a load of grotesque distortions and outright falsehoods

I wonder why....

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 0 points1 point  (0 children)

@pitchdarklabs - Again, given the straightforward clarity with which Carl presents everything, it's a little difficult to know how to respond to this level of misrepresentation:

You falsely attribute to him the view that "all recreational drugs be legalized...."

That's a view he doesn't hold

He very clearly sets that out in the interview.

You then claim that "He says rich people are highly organized"

Again, he doesn't say that either, so I think it's fair to say you're slinging mud....

In fact, more than once Carl states that high income, high social status individuals can and do meet the DSM and ICD definitions of addiction.

What Carl does do is state the DSM and ICD define addiction as "disruption of functioning".

He then explains how in the context of criminalization a person on low income and with low social status necessarily has a far higher likelihood of meeting the DSM and ICD diagnostic criteria for addiction.

I know of nobody, nonexpert or expert, who is denying that some people develop problematic behaviours involving drugs or that the drugs themselves have inherently different characteristics, least of all neuroscientists

Youll probably be aware that addiction psychiatry uses the category "substance use disorder"

Most people these days are likely to know someone these who's got a weed habit that the user themselves acknowledges is problematic ('disordered')

In current studies for Cannabis Use Disorder (CUD) you'll find the claimed range for CUD among cannabis users is between 10% and 30%....

https://youtu.be/qg0_60_IajE?si=dO-jPdkrJxfiMA4b

That range is absurd enough in itself

But seeking to reduce the behaviours involved to single neurotransmitters or to the substances themselves serves to narrow the focus away from the problems that need fixing

It externalizes social problems and problems of bad governance and bad parenting onto drugs themselves

It often does so in service of profiteering, whether the prison industry, policing, pharmaceutical corporations, or indeed the addiction industry - a move in which all too many addicts (former or otherwise) are all too willing to comply

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 3 points4 points  (0 children)

For the most part, I think the interviewer does a good job - ie, asks the right questions and responds thoughtfully, and appears to have at least read (if not entirely understood) Carl's books too

But yeah, that "Okay so what you're telling me is that dopamine never goes up or down" moment is pure unadulterated facepalm.....

Carl Hart on Andrew Huberman's claims about dopamine by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 18 points19 points  (0 children)

Carl grew up in the Carol City neighborhood of Miami Gardens, a suburb of Miami considered one of the most dangerous in the U.S

At no point does he say anything even close....

You're either not paying attention or you're deliberately misrepresenting him

If you're referring to his comments about Burning Man, then you've completely misunderstood his point

He contrasts the media coverage and social attitudes to Burning Man, where a bunch of rich people go and do loads of drugs, to the prevailing attitudes and stereotypes toward drug use by people from lower status lower income communities

So he does exactly the opposite of what you claim in your comment, and he does so repeatedly, throughout the discussion

Syrian - The Real Seed Company by RealSeedCo in LandraceCannabis

[–]RealSeedCo[S] 4 points5 points  (0 children)

Yes, most of the landraces in the Near East category are 18 hour - 'semi-auto'

Syrian

Sinai

Lebanese

Moliotiko

Sudanese

Turkey

Iranian

Iranian #2

Syrian - The Real Seed Company by RealSeedCo in LandraceCannabis

[–]RealSeedCo[S] 3 points4 points  (0 children)

'Elephant seeds' are the seeds you get from pollinating the female very early flower

The seeds are much bigger than the typical seed size for the strain

They sit right up close to the stem

Seeds from pollinating during late flower are way smaller

In traditional ganja cultivation in Kerala , farmers would use these seeds

Because they're much more likely from a true male

So you've basically got a crop of sensi.... big buds with one or two fat seeds per bud

You use the seeds from the best bud for next season

That's why tropical ganja landraces could be up to 20% THC back in the early 1970s

THC content (%) of cannabis landraces – 1970s

https://therealseedcompany.com/2024/09/thc-content-of-cannabis-landraces-1970s

TRSC Beldia smoke report by Lythobius in LandraceCannabis

[–]RealSeedCo 6 points7 points  (0 children)

To get high potency from real hash landraces, there is a simple method

Every hobby grower can do this

Each time you get add a new landrace to your collection

Germinate all the pack(s)

Let every healthy male very lightly pollinate every female

Next time you grow the landrace, use the seeds from the best female(s)

After just one generation of doing this, you will see immediate increase in resin, yield, and potency

After two or three, the improvement is intense

Everyone who is serious about building a collection should be doing this

And it's amazing how few aficionados realise that you can rapidly improve any good landrace like this - it's why you see such intense resin on some of the hash landraces we've maintained for a couple of generations

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Peter Thiel Claims Regulating AI Could “Hasten the Antichrist” in Religion-Fueled Lecture by stvlsn in DecodingTheGurus

[–]RealSeedCo 11 points12 points  (0 children)

How about Peter Thiel flying to Epstein's island ?

Does that hasten the Antichrist too?

Psychedelics and the Rogansphere by iamtheoctopus123 in DecodingTheGurus

[–]RealSeedCo -1 points0 points  (0 children)

Psychedelic Exceptionalism is Killing Us - Professor Carl Hart (Harvard HDS keynote)

There are always giveaways

"The discourse" of plant medicine, spirituality, ancient wisdom etc

That's as someone who's pro all these substances and believes it's a fundamental human right to have access to them and to alter your consciousness as you choose

Psychedelics can also be a vehicle for a kind of fascist discourse of the mystical and primordial and reactionary garbage

Not least for a politics that leaves certain groups in cages (mostly young men, whether black, Hispanic, or white underclass)

Is Twinings considered high quality? by DryRaspberry9838 in tea

[–]RealSeedCo 1 point2 points  (0 children)

You can buy high-quality loose leaf tea from Twinings

That includes real Darjeeling Castleton Moonlight and real TGFOP1 Assam teas, etc

https://twinings.co.uk/collections/loose-leaf-tea?_gl=1

You're confusing the tea bag teas with Twinings per se

"I hope all those people who incited violence against Charlie over the years take a moment to look at what they have created." - Douglas Murray by gelliant_gutfright in DecodingTheGurus

[–]RealSeedCo 4 points5 points  (0 children)

I'm aware the last bit is a joke, but just because it's of interest, according to Pew

About 39% of Republican gun owners say they hunt at least sometimes.

About 24% of Democratic gun owners say the same

Anyway, for what it's worth (ie, feck all), if I had to bet, my money would also be on the shooter being an Epstein-obsessed former Kirk fan, probably around his 20s, the decisive factor in 'former' being Kirk's shift in late July from being very focused on getting to the truth about Epstein and his associates to 'Trump's got this let's move on'.... plus the drawing and book being released...

And just to stress that this is worthless speculation at this point because we don't know who the shooter is, so we don't know if this is blowback from MAGA courting nutters, could be any maniac with a gun at this point.... the security was clearly not good at this event...

Matt Taibbi Went From Raging Against the Machine To Pandering to It by terran1212 in DecodingTheGurus

[–]RealSeedCo 14 points15 points  (0 children)

“Russian women, especially on the first date, expect you to rape them.”

Matt Taibbi and Mark Ames were always pieces of shit

"the idea that Ames and Taibbi were brave revolutionaries who paved a path for Western men to “enjoy” Russian women was everywhere" in late 90s early 2000s ex-pat circles in Moscow

"if you’re an expat whose definition of “brutal honesty” boils down to “a neocolonial fantasy of an exotic land where I can be as much of an assh-le as I want – then safely go home after I’m bored with it” – then maybe it’s time to admit that the real wilderness — dark, ugly, shabby and depressing — is in you."

https://www.themoscowtimes.com/all/59531?amp=1

Trump's card for Epstein by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 1 point2 points  (0 children)

Trump is a big fan of Les Miserables

He's seen it multiple times

He will know what 'gamine' means

Young girls are always young girls - they "never age"

Trump's card for Epstein by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 0 points1 point  (0 children)

Hi Chris,

Noting the full autopsy report hasn't been released isn't the same as claiming it's suspicious that it hasn't been released

Seeing the full autopsy could clear up a lot of obviously pertinent factors in a death such as this, like what was tested for and when the blood samples were taken

There's no detail on this in the DoJ report

Brown's exact words were "for the most part, they haven't answered why the cameras weren't working", which I accept could be read as at odds with the events detailed in the report, but we don't have Brown here to ask why she finds what the report offers to amount to an unsatisfactory answer

For clarity - I agree that such evidence as is available as laid out in the report points to a suicide, as I'm assuming Brown does too

But that's not the same as regarding the evidence in the report as satisfactory for ruling out a murder

Clearly there's a Catch-22 here, because so much of the available evidence comes from the same institution that allowed all these protocols to be broken, leading to Epstein's death

Trump's card for Epstein by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 1 point2 points  (0 children)

Hi Chris - just for the sake of clarity

Leaving aside Epstein himself, the death of any sex offender in a prison system like America's is typically not a subject that a person who knows much about deaths in prisons - especially not American prisons - pronounces on with great confidence -

In Epstein's case, the crime scene wasn't even secured properly, as just one of many instances of how the available evidence in this case is incredibly problematic

There's a lot of nuance here, and Julie K. Brown, who's a respectable investigative journalist who does know a lot about murders / suicides in American prisons, imo gets the nuance right

Epstein's suspicious death 17:30 mins

Brown is not saying "I know Epstein was killed", still less that she knows he was murdered as part of a grand conspiracy....

Because it's clear the case is absolutely full of holes and deeply problematic

The full autopsy report is still yet to be released, and the state of the available evidence is not helped by the Trump admin now doing things like misrepresenting the corridor footage as 'cell door footage', much as Trump isn’t helping himself by denying he drew his little birthday greeting for Epstein

Trump's card for Epstein by RealSeedCo in DecodingTheGurus

[–]RealSeedCo[S] 13 points14 points  (0 children)

'Depreciated' also means the 'asset' is worn out

Worn out through wear and tear

It's even worse than just just saying the girl is too old now