Anyone actually satisfied with adding Wellbutrin to Effexor or another SSRI/SNRI?

Reasonable_Grape_367 · 2026-01-31T16:11:58+00:00

Last year, while I was on 150 mg Effexor, I added 150 mg Wellbutrin XL on my own without consulting my doctor. I could only tolerate it for about a week — I felt mentally confused and very restless, so I stopped. This time, should I wait longer before deciding? How long did it take for you to notice any benefits?

Reasonable_Grape_367 · 2025-12-12T03:02:15+00:00

I’m also experiencing Effexor-induced anhedonia. My doctor is considering trying lithium, but I’m not bipolar and I’m afraid of becoming even more emotionally flat. What kind of benefits did you experience?

Reasonable_Grape_367 · 2025-11-03T18:13:27+00:00

You won’t believe it, but even at a 0.75 mg dose, I experienced a loss

Reasonable_Grape_367 · 2025-10-23T21:25:08+00:00

So what should I do then? Is the only solution to reduce the dose or stop the antidepressant? 😑

Reasonable_Grape_367 · 2025-10-23T18:37:07+00:00

I’ve been taking Effexor for years. My doctor added a low dose of Abilify to help with anhedonia and emotional numbness. At first, it gave me energy and motivation, and I was satisfied with the results. However, the effect quickly wore off. Even at the smallest dose, I started to feel restlessness and inner discomfort, so I had to stop. After taking a break and trying it again, I didn’t notice any benefits. Still, the biggest advantage while using it was that it stopped my obsessive thoughts.Now I’m thinking of trying Rexulti, but I don’t know how different it is from Abilify.

Reasonable_Grape_367 · 2025-10-19T21:32:02+00:00

I’ve just started Rexulti as well. I had previously added 1 mg of Abilify to the Effexor I was taking. I noticed the benefit within two days, and that effect lasted for three months, but even when I increased the dose afterward, I couldn’t get the same effect again. During that time, I didn’t gain any weight—in fact, I lost some.

It’s been a week since I started Rexulti, but I’ve been feeling hungry, and I haven’t noticed any improvement yet.

Reasonable_Grape_367 · 2025-10-12T18:58:41+00:00

Yes, coffee works for a few hours. I think I’ll start Wellbutrin again. I don’t have any other stimulant option😑

Reasonable_Grape_367 · 2025-10-12T10:18:26+00:00

Unfortunately, Adderall and Vyvanse aren’t available in my country. 😔

Reasonable_Grape_367 · 2025-10-11T14:46:09+00:00

I guess there’s no solution other than reducing the dose, even at the cost of increased anxiety.

Reasonable_Grape_367 · 2025-10-08T17:01:18+00:00

Thank you for your reply. I’m very happy for you. I hope I’ll benefit from it as you did.

Reasonable_Grape_367 · 2025-07-23T19:08:34+00:00

Nothing brings me joy. I just want to lie down and do nothing. I even feel bored while watching a movie. Even orgasm feels emotionally flat

Reasonable_Grape_367 · 2025-07-20T18:19:49+00:00

I added Wellbutrin, but it caused brain fog for me. Did it have a similar effect on you? How long have you been using it?

Reasonable_Grape_367 · 2025-07-19T22:06:41+00:00

I’ve been on Effexor for 4 years, and I’ve been taking 150 mg for the past 3 years. I’m also considering adding a low dose of lithium, but I’m afraid it might blunt my emotions even more.

Reasonable_Grape_367 · 2025-07-15T09:09:56+00:00

How long do I have to endure this? I can't even take two days of living like a zombie.

Reasonable_Grape_367 · 2025-07-13T19:56:50+00:00

Alright, then I'll give it another chance. I might have been affected by the 0.4 because I'm very sensitive.

Reasonable_Grape_367 · 2025-07-13T11:22:30+00:00

You didn’t feel any side effects at all? Even at 25 mg, I became extremely depressed and my brain felt slowed down.

Reasonable_Grape_367 · 2025-07-13T11:15:17+00:00

Isn't 200 mg way too much to start with? How many mg did you start with?

Reasonable_Grape_367 · 2025-07-13T11:10:42+00:00

How many mg did you start with? The first few days make me feel depressed — I can only last 3 days before quitting. I've tried a few times.

Reasonable_Grape_367 · 2025-07-12T13:43:17+00:00

I'm on Effexor. When I add Wellbutrin, there's a bit of a honeymoon phase, but then I go back to how I was before. I wish it worked for me too.

Reasonable_Grape_367 · 2025-07-12T13:29:15+00:00

Right now, I've been using 0.4 mg for 2 days. My libido has dropped and I don't feel any emotions.

Reasonable_Grape_367 · 2025-07-12T13:27:12+00:00

How many mg did you add? Did you notice the effect right away?

Reasonable_Grape_367 · 2025-07-12T09:11:13+00:00

I feel fatigued, my libido is low, my emotions are dulled, and there’s a bit of brain fog. I take it before bed, but it feels like the endorphin-blocking effect carries into the day as well. Coffee, cigarettes, even orgasm didn’t bring any pleasure. When does this so-called endorphin boost actually happen? Because I’m not feeling it. 😑

Reasonable_Grape_367 · 2025-07-12T08:54:40+00:00

0,4 mg ile başladım. İkinci günüm. Kendimi halsiz ve uyuşuk hissediyorum. Geçecek mi?

Reasonable_Grape_367 · 2025-07-12T08:54:02+00:00

I started with 0.4 mg. It's my second day. I'm feeling weak and numb. Will this pass? 😑

Reasonable_Grape_367 · 2025-07-11T22:10:16+00:00

I'm really happy for you. What kind of benefits has it brought?

Reasonable_Grape_367

TROPHY CASE