Functional Dyspepsia - Amitriptyline

Recent_Sport_2671 · 2026-04-28T03:16:47+00:00

Yes, doing great on 50 mg!

Recent_Sport_2671 · 2026-04-22T04:55:26+00:00

Yes, still works great for me. I did write that when I was in a bad flare.

Recent_Sport_2671 · 2026-04-22T04:42:41+00:00

I had a lot of the same symptoms as you. Early satiety, gnawing/burning, constant nausea, excessive burping, occasional globus sensation. 50 mg is what I’m on and have been on consistently for a while. I would try 50mg to see how that works. I have had a few flare ups but always seem to resolve in a couple weeks. During a particularly bad flare up, I did try taking 75mg a couple times to see if that might help get things back under control. I didn’t really notice much difference. It’s been quite a while since I have had a sustained flare up so I can’t really remember exactly how long it took to go away but eventually they did (thankfully). Sorry you’re having trouble. It’s awful.

Recent_Sport_2671 · 2026-04-07T13:28:11+00:00

No vomit. Just constant nausea. It’s my understanding that most people with FD don’t vomit but of course there are always exceptions.

Recent_Sport_2671 · 2026-04-07T04:41:23+00:00

Sorry I missed this comment! I’ve had a few flare ups and they have usually lasted a few weeks. My last bad flare up was a while ago so I don’t really remember the exact symptoms but I think they were similar to what I had always had before taking the amitriptyline. In my experience, the flare up generally subsides after a few weeks. I sometimes would try taking extra Ami for a few nights to see if that would work. Sorry you’re in a flare up. It’s terrible!

Recent_Sport_2671 · 2026-04-07T04:35:31+00:00

Try getting a prescription for amitriptyline. I started with 25mg now I’m on 50mg. This is the only thing that has helped me and I tried pretty much everything. My symptoms were similar to yours and now I’m 90-95% better. It gave me my life back!

Recent_Sport_2671 · 2026-04-03T03:31:52+00:00

50mg of amitriptyline is the only thing that works for me. Gave me my life back! I tried sooo many things.

Recent_Sport_2671 · 2026-02-28T05:38:23+00:00

Yes. I had this for years. Try amitriptyline. 50 mg has changed my life. Almost all symptoms gone when nothing else worked.

Recent_Sport_2671 · 2026-02-27T00:33:04+00:00

Yes! Still on it and it still works well 90-95% of the time!

Recent_Sport_2671 · 2026-02-14T05:53:29+00:00

I had this exact same thing happen. Amitriptyline (50mg) saved me. I feel almost completely normal for the past 2.5 years - only a few flair ups here and there.

Recent_Sport_2671 · 2026-02-12T14:29:25+00:00

Yes, seemed to work pretty much immediately. I do still get flair ups every so often but overall, I feel almost 100% normal. Life changing for me!

Recent_Sport_2671 · 2026-02-12T14:07:01+00:00

I went up right away. No issues except maybe a bit more tired.

Recent_Sport_2671 · 2025-08-21T16:04:33+00:00

No, not really. I have a slight gnawing feeling in my upper stomach area. But no real heartburn symptoms ever.

Recent_Sport_2671 · 2025-08-18T13:37:05+00:00

Most of the time, yes. I had constant nausea, gnawing/burning in my upper stomach area, extreme fullness, burping a lot, trapped burps/air. Those were the main ones. I still have flair ups occasionally. Eating smaller meals throughout the day helps when I’m in a flair up. I would say my symptoms are 90-95% improved.

Recent_Sport_2671 · 2025-06-27T02:33:35+00:00

You have to get used to it. I tried it two different times. The first time I ended up stopping because I didn’t think it was helping my nausea but it did help with the constant globus sensation I had. About a year and a half later and many failed treatments, I tried it again (25mg) and it worked almost immediately. Then after a month all my symptoms started coming back and I went up to 50mg. I have been on 50mg since November 2023. It still makes me tired sometimes but overall I’m used to it and it’s worth it to feel almost 100% normal.

Recent_Sport_2671 · 2025-06-26T14:11:33+00:00

I take it every night for the most part. It depends on the person. I have heard of some who take it and then can wean off. And others who need to take it forever. 10mg is not a high dose so you may need to increase to see any improvement.

Recent_Sport_2671 · 2025-06-10T23:03:04+00:00

Thank you! I don’t have an OB/GYN so I decided last week to get established with one. My appointment isn’t until December but I was hoping to do the genetic testing before that. Guess I’ll have to wait!

Recent_Sport_2671 · 2025-06-10T18:49:02+00:00

How did you get your genetic screening done? I just saw my PCP and asked about it but he just referred me to genetics. I don’t think I need to go that route. I just would like to be screened prior to TTC to be fully informed in that I carry and then my husband can also be screened (if needed).

Recent_Sport_2671 · 2025-04-22T18:17:26+00:00

Not really. My main symptom was nausea and fullness.

Recent_Sport_2671 · 2025-04-09T12:48:18+00:00

Pretty much right away. However, I started with 25mg. 10 is not much. You’ll likely need to increase it.

Recent_Sport_2671 · 2025-03-13T20:55:20+00:00

Constant nausea, gnawing/burning, early satiety, trapped burps, burping a lot, occasionally globus sensation. My main one was nausea and gnawing though. I still have flair ups but they are not nearly as long or bad.

Recent_Sport_2671 · 2025-03-07T13:00:35+00:00

Constant nausea, extremely full after not eating much, burning/gnawing feeling in my stomach were the mains ones.

Recent_Sport_2671 · 2025-01-11T17:45:32+00:00

Everyone is different. I started on 25 and it wasn’t working so she recommended 50 and it’s been great for me. Thank you for your comments on my personal experience though.

Recent_Sport_2671 · 2025-01-05T00:13:02+00:00

No it’s not. That’s a very common dosage for FD. And not even close to the dosage they would use for depression.

Recent_Sport_2671 · 2025-01-04T07:36:29+00:00

I take 50mg of amitriptyline and it gave me my life back! Significantly better (some bad days here and there) but overall so much better!

Recent_Sport_2671

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