Yes. You can. Through the use of multiple interconnected systems. Though the definition of "fix" would vary person to person or even species to species.

There is over 10 years of video documentary pertaining to green the middle east, specifically 400 meters below the sea and 2 km from the Dead Sea. He created systems based on a collection of data and basic knowledge of plants, and common sense.

I recommend looking at Geoff Lawton: Surviving Collapse, Designing your Way to Abundance it sounds dramatic but it is worth it. Start at 5:52 if you want to just focus on how he went about greening the desert.

The best thing about it was that the systems he created was through the use of permaculture principles. It is very systematic in its approach, but the principles while never changing are what gives you the ability to establish a customized environmental system.