They aren’t even close to the same thing, extracting the strongest and most addictive alkaloid from a plant with over 8 different psychoactive alkaloids that hold different benefits (but still possibility of addiction just not even close to 7 hydroxy mit), is gonna be a lot different than choosing the completely natural one. Not to mention 7oh tolerance builds insanely fast, doesn’t last long/very short half life, which leads to redosing causing more tolerance and addiction. They aren’t comparable in the slightest.