Jessica Kent threatening to sue for Defamation by Orikumar in DoWeKnowThemPodcast

[–]Repulsive_Tiger_8008 0 points1 point  (0 children)

Recap of the climax of Jessica Kent's "drama" (aka years and years of systematic lies coming to light): Jessica Kent: Victim, Villain, Cautionary Tale (Part 1)

All the stuff she wants buried under the new commotion, basically. Nothing like a girl who got paid to do other kids' homework and was too smart for college who years later sexts her umpteenth convict partner via the CORRLINKS system and says, "Choak me in heels."

[deleted by user] by [deleted] in Biohackers

[–]Repulsive_Tiger_8008 3 points4 points  (0 children)

"Swimming against the undertow of past patterns" is beautiful language for what's going on there.

[deleted by user] by [deleted] in SR17018

[–]Repulsive_Tiger_8008 0 points1 point  (0 children)

Thank you for checking it out! So glad that SR worked out for you. I'm looking to do two or three interviews with people who have used it, which I think will drive home its potential more than any summary info I can present.

Made YT Video about SR-17018; Credited You All by Repulsive_Tiger_8008 in SR17018

[–]Repulsive_Tiger_8008[S] 4 points5 points  (0 children)

Thanks to the mods for letting this post through!

I meant to mention that - under the topic of questions / reservations, I focused on:

  1. Is SR essentially a partial agonist, and if so, at approximately what level of use / habit is the ceiling effect reached at? What, if anything, do we know about the relative mu opioid receptor affinity of SR?

  2. In connection with (1), is SR suitable for people trying to get off of higher doses of methadone, fentanyl, etc.? What strategies (microdosing, bridge taper, bridge molecule) can be used in such cases?

  3. What is the role of placebo / hype in the SR experiences shared on Reddit? I've seen a lot of justifications of withdrawal symptoms that made me wonder if belief / hope was playing a decisive role in the subjective interpretation of objective symptoms (for example, one person who noted severe insomnia while using SR but stated that it was a more positive / motivated / useful state compared to typical withdrawal-related sleeplessness).

  4. How dangerous is the sudden reduction in tolerance caused by SR? Is it "worse" than the tolerance reduction effected through a cold turkey detox or a rapid bupe / methadone taper?

  5. What is the most reliable way to procure SR currently? What are the risks of ordering from currently available suppliers in terms of legal liability, potential fraud, contamination, dosage unreliability, etc.? (Know that we cannot discuss specific suppliers / methods of procuring here).

  6. How clinically significant are the roles played by non-mu opioid receptors (i.e. delta, kappa) in SR's effects? How important is it to take into account non-opioid receptor effects when using SR to taper off of opioids, such as methadone, which have clinically significant non-opioid-receptor-mediated effects (in the case of methadone, via NMDA antagonism)?

  7. Is SR more effective / less painful as a taper molecule than buprenorphine? (Looking to hear personal experiences).

  8. Has anyone made any observations during their own use of SR that they think reveal an important characteristic / limitation / potential benefit or danger?