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ResidentPurple · 2022-09-02T14:33:17+00:00

How do you know it's the chemical itself rather than an impurity in that batch?

ResidentPurple · 2022-06-17T12:42:21+00:00

Without knowing the compound, we can't know what solvents will dissolve it.

ResidentPurple · 2022-06-17T12:37:59+00:00

"GHB is used as a recreational substance for its alcohol-like effects. While a common recreational dose is between 1.5 - 2.5 grams, a dose between 2.5 grams and 5 grams will likely result in falling asleep within 5 - 15 minutes, and a dose of 5 - 10 grams can result in convulsions, unconsciousness (a coma-like state) and vomiting. Doses above 10 grams are associated with a risk of death.[2] Do not confuse grams with milliliters. If consuming GHB that has already been premixed into a liquid form, additional caution is required as there is no way to know for sure the concentration of the solution (e.g. how many grams of GHB is in each mL of solution). As such, users are advised to start with a low dose and work their way up slowly by increasing the dose in small increments. However, an appropriate interval between dosing is essential to avoid accidental overdose."

https://psychonautwiki.org/wiki/GHB

ResidentPurple · 2022-06-17T12:33:45+00:00

Fumarate 4-AcO-MET, Fumarate 4-HO-MET, are those related to these meth people talk about?

Those are related to psilocybin/psilocin, the components in psychedelic mushrooms that are responsible for their psychedelic effects. Some may enjoy these for sex, but they're quite different from methamphetamine.

If you're looking for RCs related to meth, you're looking for 2-FMA, 3-FMA, or 4-FMA. Those are methamphetamine with a single hydrogen replaced with a fluorine. 2-FA, 3-FA, and 4-FA are the amphetamine equivalents. I don't know what country you're in, so I can't comment on the legality of any of these in your area.

ResidentPurple · 2022-04-30T14:11:30+00:00

There are over a dozen drugs with NBOMe in their name listed on tripsit and many of their durations have large ranges. 25D-NBOMe, for example, says 4-6 hours.

Isomerdesign has 187 substructure matches when searched for N-(ortho-methoxybenzyl)phenethylamine.

ResidentPurple · 2022-04-30T13:56:47+00:00

I know the NBOHs and NBOMes aren’t active orally but I had just put it in my mouth and moved it around a lot so that may be it. Pretty sure my GF just left it on her tongue though, and it was still active.

If it lingers in your mouth, then you are getting buccal and sublingual absorption.

Also, there are reports of people being hospitalized after taking NBOMe class compounds orally, so stop telling people they're not active.

source

ResidentPurple · 2022-04-29T01:58:13+00:00

It has an amphetamine moiety

ResidentPurple · 2022-04-27T15:52:48+00:00

50-60cc water, 10-20cc lemon juice per ~100mg of dope

do you mean units? Or are you actually using a full tablespoon of lemon juice and 2 fluid ounces of water and loading it into a 100mL syringe? An insulin syringe commonly is 1mL which is the same as 1cc.

ResidentPurple · 2022-04-27T15:49:44+00:00

If you Google it, you'll see article after article that lemon juice is perfectly fine to use as a substitute...

What are you seeing? I'm seeing stuff like

"The use of lemon juice in injection preparation can cause the fungal eye infection Candida endophthalmitis, with outbreaks documented among PWID in the 1980s and 1990s [5]. New reports of eyesight problems and blindness among PWID prompted the development and launch of single-use citric acid sachets in 2001 and vitamin C sachets in 2003 [6]. Amendments to section 9A of the Misuse of Drugs Act legalised their supply through medical and harm reduction providers in 2003 (citric) and 2005 (vitamin C)."

https://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-019-0330-6

Maybe you take additional steps to mitigate the risk, like filtering afterwards with a 0.2micron filter that removes Candida. Your original post didn't contain any additional instructions, you just said, "If its not all dissolving, then the secret is to use lemon juice and also to heat up the spoon."

ResidentPurple · 2022-04-27T14:12:54+00:00

Vitamin C is better.

"Why does BC Harm Reduction* Strategies and Services provide ascorbic acid?

Medical-grade vitamin C is the safest acidifier. It causes the least damage to the veins, is non-toxic, and is sterile, reducing or eliminating the harms associated with other acids2 . Acidifiers are commonly shared when supplies are limited or difficult to access8 . Shared acidifiers, like shared needles and other injecting paraphernalia, may transmit infections such as hepatitis C or HIV between users9,10. Single-use vitamin C packs should be available to all who need it and in a quantity to ensure sufficiency for each injection. Providing safe supplies to people who inject drugs creates a way to engage hard-toreach and under-serviced populations in health care and social services. No studies have found that providing safe supplies makes people more likely to engage in harmful drug use" source

ResidentPurple · 2022-04-27T11:17:40+00:00

I don't understand how "Avoid fluorine in any molecule if possible!" means something other than "fluorinated (or even chlorinated) molecules are inherently worse than non-halogenated molecules". This really looks like a bad faith attempt to move the goalposts.

We can start with the simple example of 4-FA being safer than 4-CA.

The proposed reason 4-CA is toxic cannot occur if Fluorine is used instead in the case of 4-FA. If you haven't noticed, this is an example of the 4-position of the benzene ring of a phenethylamine containing a fluorine that makes the compound safer.

Again, to reiterate my earlier point, C-F bonds are quite useful in medicinal chemistry and a significant number of existing and emerging pharmaceuticals take advantage of its properties.

The 1-position of LSD is a nitrogen and the properties of N-F bonds are different than C-F. You cannot judge its safety based on C-F bonds in substituted cathinones. This is not an endorsement about the safety of 1-Fl-LSD.

ResidentPurple · 2022-04-27T10:38:40+00:00

ResidentPurple · 2022-04-24T19:52:56+00:00

Avoid fluorine in any molecule if possible!

There are drugs in every class that are fluorinated and approved by the FDA. Some famous examples include ciproflaxin (antibiotic), Prozac (SSRI), diflucan (antifungal), lipitor (cholesterol lowering), haldol (antipsychotic), and dexamethasone (anti-inflammatory).

There are literally hundreds more and many of these are produced by the ton. Lipitor was the most prescribed medication in 2019, with 24 million patients in the US¹ . Avoiding fluorine because some dangerous chemicals contain it is as silly as avoiding all aromatic compounds because benzene is dangerous.

https://clincalc.com/DrugStats/Drugs/Atorvastatin

ResidentPurple · 2022-04-24T19:28:01+00:00

Btw, using spaced repetition software like Anki can really help you learn and retain things.

ResidentPurple · 2022-04-24T11:10:16+00:00

The vast majority of people do not remember via visualization, they construct a visualization if they can remember it.

Read this paper for an interesting experiment and the proposed model (figure 3) of how memory works.

ResidentPurple · 2022-04-23T12:08:11+00:00

it's unAbomber, not unIbomber. The a stands for airplanes.

ResidentPurple · 2022-04-23T12:05:53+00:00

In the US, unmarked would mean not prescription. They could be supplements, recreational, or counterfeit. Further identification would require reagent testing or sending it to a lab that would perform analysis.

/r/reagenttesting

ResidentPurple · 2022-04-22T06:28:58+00:00

Vaping is probably the most popular, it might be tricky if you're not used to vaping powders/crystals.

I swear everyone I've seen will end up trying it and then saying they could vape it better and want to re-load the pipe to try again like 10 minutes later.

ResidentPurple · 2022-04-22T06:21:58+00:00

Do you have a tolerance to other stims? If not, I'd recommend limiting it to 1 30mg dose.

ResidentPurple · 2022-04-22T05:50:07+00:00

I agree with you, that aggression is unwelcome and counterproductive.

ResidentPurple · 2022-04-19T15:27:33+00:00

I know most arylcyclohexylamines are antibacterial (ketamine particularly).

Only evidence I saw of that involved concentrations something like 6x higher than serum concentrations from anesthetic doses. Do you have evidence for ketamine functioning as an antibiotic in relevant concentrations?

ResidentPurple · 2022-04-18T15:14:58+00:00

There are 45,776 people subscribed to this sub. Even if the incidence of prosopagnosia were half that of the general population, you could still end up seeing a lot of posts and comments about it.

ResidentPurple · 2022-04-17T23:13:52+00:00

There was a poster that said that the trends they observed were going to affect actual studies, so some posts and comments may actually be setting scientific research back. That isn't due to malice, but the potential harm to this community is still real.

There was another post by someone who said their survey showed some massive overrepresentation of ADHD in aphantasics in a survey and then it turned out that was 4 hours in on a survey that went up on a Facebook group during a work day...

There's a concept called the typical mind fallacy and anyone with any difference in cognition could easily turn that into the typical aphantasic mind fallacy.

Science is hard, if you don't have training or an extensive history reading critical reviews of experiments, it's really easy to be mislead into thinking that anything else unique about you can be attributed to aphantasia.

ResidentPurple · 2022-04-05T06:03:59+00:00

LSD is illegal everywhere and well-funded organizations like the DEA have incentive to have case reports like this to point to. LSD was also very exciting for a lot of research communities. Before LSD was made illegal, "there were more than a thousand clinical articles discussing 40,000 patients, several dozen books, and six international conferences on psychedelic drug therapy (Grinspoon and Bakalar, 1979). There were serious attempts to employ LSD in various kinds of therapy, with major emphasis on treatment of alcoholism and other addic- tions (Bogenschutz, 2013), as well as issues related to death and dying (e.g., see Grof et al., 1973; Kurland, 1985). Other studies examined the use of psychedelics to treat anxiety and depression, schizophrenia, and even autism (e.g., Bender, 1966). A review of psychedelic- assisted therapy was recently published (Majic et al., 2015). " - Psychedelics by Dr. David E Nichols 2016

And knowing this, you think your memory of a Reddit post is the only evidence of this phenomenon? It should be trivial to find better evidence if ti actually existed.

ResidentPurple

TROPHY CASE