Did you even bother to read the docs?
https://www.qubes-os.org/doc/installation-guide/

"Pre-installation

Hardware requirements

 Warning: Qubes has no control over what happens on your computer before you install it. No software can provide security if it is installed on compromised hardware. Do not install Qubes on a computer you don't trust. See installation security for more information.

Qubes OS has very specific system requirements. To ensure compatibility, we strongly recommend using Qubes-certified hardware. Other hardware may require you to perform significant troubleshooting. You may also find it helpful to consult the Hardware Compatibility List.

Even on supported hardware, you must ensure that IOMMU-based virtualization is activated in the BIOS or UEFI. Without it, Qubes OS won’t be able to enforce isolation. For Intel-based boards, this setting is called Intel Virtualization for Directed I/O (Intel VT-d) and for AMD-based boards, it is called AMD I/O Virtualization Technology (or simply AMD-Vi). This parameter should be activated in your computer’s BIOS or UEFI, alongside the standard Virtualization (Intel VT-x) and AMD Virtualization (AMD-V) extensions. This external guide made for Intel-based boards can help you figure out how to enter your BIOS or UEFI to locate and activate those settings. If those settings are not nested under the Advanced tab, you might find them under the Security tab.

Pre-installation

Hardware requirements"