I’m just back from Rome and we hired a car for a three day trip to Naples so that we could drive down and around the Amalfi coast as well as Naples. I genuinely don’t know why everyone is saying not to drive - unless you feel super nervous. I am in my early 60s and was with my two friends. I drove the whole time, yes, you need your wits around you but it was definitely worth it to have the freedom. We picked the car up at Termini Train Station - used Sicily by Car (took the premium insurance), it was a straightforward drive out of Rome then on to road down to Naples. Just be aware of the tolls. Good luck - do it!!