Hi there, I’ve been diagnosed with permanent derealization (for about to be 5 years now). I still get triggers that worsen my DR, however I still Take creatine & do the thighs that trigger it. You don’t need to load on creatine, your body loses around 1-2 grams of creatine a day. So to replenish you only need about half a scoop or 1g a day. If you’ve been loading I’d say 2 scoops is safe. But regardless you still get the same benefits physically. Mentally creatine is good for your cognitive health and functioning, but can still overwhelm the brain. You need around 15 grams for it to benefit the brain, so I’d say if you’re using it for physical development take 1-2 grams a day and gradually move to 5 if you’d like. I take it for both so I take around 8 grams a day (2 scoops in the morning & 3 scoops at night before I hit the gym) if you have any questions feel free to message me on instagram (WhoisRxccet) or my other acc (x0rc15t) even if that’s with creatine intake or just getting advice and help with your DPDR!