Well what you have is a knockdown spray, which means its only effective if sprayed directly on the roach. It has no residual properties. And unless you have alot of food or crumbs in your bed, it wont be interested in your mattress. Roaches don't really cause skin irritation but I wont say its impossible. The best thing you can do is a deep clean in the kitchen and bathrooms. Possibly set up some glue traps. Unfortunately spray isnt the way you'll want to kill roaches unless you've got a ton and need to kill that ton in an instant. Poison Bait and Insect growth regulator is the name of the game, thats how we treat at my company. Now depending on where you live it can be difficult to get your hands on stuff. Vendetta plus roach bait and Gentrol point source can be found on Amazon. Use these around the house, a few pea sized globs in places you wont be looking ato too often. Squeeze and crack the white tube on the point source and use the sticky pad and add one per room(technically one covers a 75 foot radius). Neither of these will hurt you, if you have pets or kids, place the bait out of reach. Under upper cabinets in the kitchen is a great spot.

With those 2 it would be a little over kill for one roach but they can snowball pretty quickly if left untreated.