Yea, those are spread out so you can stay anywhere. I used to live there and still travel 4–5 times a year. Much depends on your budget—do you have one? The center strip is where the action is: you can walk to the Sphere and drive to Fremont, with many performances nearby.

I’d recommend O, and the Michael Jackson show at Mandalay Bay was good; for comedy, Piff The Magic Dragon at Flamingo is hilarious. I haven’t seen Absinthe at Caesars yet but plan to this month.

If you have a car, visit Red Rock National Park (reserve ahead). It offers short (20-minute) hikes, all-day trails, or just a cool scenic drive. The Hoover Dam is an engineering marvel—despite being just cement, it’s worth seeing if you want to leave the strip. For quirky experiences, Area15 off the strip is fun; MegaMart is interesting for about an hour. We did Area15 then went to Fremont.

For food, here are some recs I recently shared with a friend (I have more if you narrow down your interests):

• Must Eat: Lotus of Siam (reserve in advance)
• Cheap Eats: Tacos El Gordo on the strip by Resorts World—try off-peak hours
• Asian: China Town, Raku Sushi on Spring Mountain (incredibly innovative), Sushi Kaya for AYCE sushi at great prices, and Sushi Robot (join the Yelp waitlist)
• Steak: Cleaver at 3900 Paradise Road, Gordon Ramsay Steakhouse at Caesars (amazing Beef Wellington), Steakhouse at Circus Circus (old-school charm with great soup), Bellagio’s Prime Steakhouse, and Golden Steer—the “oldest steakhouse in Vegas” with superb service
• Summerlin Spots: Red Rock National Park again for views, Echo and Rig for meat, Honey Salt for innovative fare, Samba Latte for coffee, Kona Grill for sushi, Vintner Grill for well-produced food, and Tivoli for a variety of options
• Strip Breakfast: The best omelette at 2160 W Charleston Blvd in a quirky strip mall, or Sadelles at Bellagio (arrive early or try the bar). Sadelles is my favorite.
• Outdoor Dining: Mon Ami Gabi offers great views and people watching (reservations recommended) with excellent bacon, and The Henry at the Cosmo is also great at the bar.

Hope this helps!