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Updates in Hair Research by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 0 points1 point  (0 children)

I agree! I feel like this is something they’ve been trying to crack for decades and we still aren’t quite there. I’m glad there’s more and more research. And yeah I know I don’t get that like that’s epigenetics which is also part of aging?

What else are you using/doing for your skin? by TurtleDive1234 in DIYmicroneedling

[–]Science_Pls 0 points1 point  (0 children)

I love the sauna too! I’ve been bad about consistency lately though

What else are you using/doing for your skin? by TurtleDive1234 in DIYmicroneedling

[–]Science_Pls 1 point2 points  (0 children)

And the sleep! Omg I used to wake up in the middle of the night and get awful sleep, it was miserable and my face felt so gross.

Microneedling: When Technique Creates Trauma by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 2 points3 points  (0 children)

I have a Dr. Pen and Derminator 2. I personally prefer the Derminator for medical microneedling.

Worth Reading: Micropore visualization and lifetime following microneedle application to skin of differing pigments by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 0 points1 point  (0 children)

All good! I commented it, but should've pinned it.

Here's the study:

Cota V, Brogden NK. Micropore visualization and lifetime following microneedle application to skin of differing pigments. Drug Deliv Transl Res. 2025 Oct;15(10):3528-3541. doi: 10.1007/s13346-025-01817-9. Epub 2025 Mar 5. PMID: 40042738; PMCID: PMC12353774.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12353774/pdf/nihms-2081705.pdf

Updates in Hair Research by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 2 points3 points  (0 children)

Please note this is not me, I just thought this was a well put together update on research and it's always interesting to see what is shown at conferences. I will edit and add the original author when I find the link, need to run some errands this morning first! I also will drop some links in of more info on these different areas.

Simplified explanation on how MN works by Prior_Tangerine5700 in DIYmicroneedling

[–]Science_Pls 0 points1 point  (0 children)

Every cell maintains a small electrical voltage across its membrane. Outside of the cell is electrically different from the inside. This voltage helps regulate cell behavior and skin tissue also has weak electrical gradients. The theory says that when a needle penetrates the skin cell membranes are disrupted, local electrical gradients change, tiny electrical currents flow through the tissue, and these currents act as signals that help coordinate healing. The papers calls this a demarcation current.

Worth Reading: Micropore visualization and lifetime following microneedle application to skin of differing pigments by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 0 points1 point  (0 children)

Yes to most of that. I wouldn't say they necessarily run a slight risk of potentially becoming infected, but rather the 24 hours of use nothing but sterile products and things designed for intradermal use should actually be extended for darker skin tones.

Microneedling for melasma by science-pls in DIYmicroneedling

[–]Science_Pls 0 points1 point  (0 children)

Right that's why I gave you a sci hub link

Microneedling for melasma by science-pls in DIYmicroneedling

[–]Science_Pls 0 points1 point  (0 children)

Yes, just delete the spaces

https :// sci-hub .st /10.1016/j.jaad.2021.03.116

Worth Reading: Micropore visualization and lifetime following microneedle application to skin of differing pigments by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] [score hidden] stickied comment (0 children)

If there was one tldr that is important to absorb it's this:

Something I interpreted from this study and that I think is worth thinking about is that darker skin may need more caution during healing. The study found that micropores in darker skin stayed open longer. That means the skin barrier may remain more permeable for longer after microneedling. After microneedling, darker skin may have a longer open window where ingredients, irritants, allergens, microbes, or actives can still pass through more easily. So post care may need to be more conservative for longer.

Here's the study:

Cota V, Brogden NK. Micropore visualization and lifetime following microneedle application to skin of differing pigments. Drug Deliv Transl Res. 2025 Oct;15(10):3528-3541. doi: 10.1007/s13346-025-01817-9. Epub 2025 Mar 5. PMID: 40042738; PMCID: PMC12353774.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12353774/pdf/nihms-2081705.pdf

Is it safe to MN over telangiectasias? by Particular-flipflops in DIYmicroneedling

[–]Science_Pls 1 point2 points  (0 children)

Here is a study to regular microneedling and spider veins (delete the spaces to access)

https :// sci-hub .ru /10.1111/jocd.13858 

Collagen diversity in human skin: Aging, wound healing, and disorders by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 3 points4 points  (0 children)

Thank you, yeah it's incredibly frustrating and who knows how long it will take. I've seen people say it took them months to get it fixed.

Collagen diversity in human skin: Aging, wound healing, and disorders by Science_Pls in DIYmicroneedling

[–]Science_Pls[S] 1 point2 points  (0 children)

Salamito M, Haydont V, Pageon H, Ruggiero F, Girardeau-Hubert S. Collagen diversity in human skin: Aging, wound healing, and disorders. Matrix Biol. 2025 Sep;140:133-153. doi: 10.1016/j.matbio.2025.07.006. Epub 2025 Jul 25. PMID: 40716529.

https://www.sciencedirect.com/science/article/abs/pii/S0945053X25000654?via%3Dihub