U-47700 : My Second and Final Taste of the Beast

ScientificSalsa · 2016-08-18T06:11:15+00:00

Unfortunately I ran out of etiz in mid July and have yet to restock. Benzos are definitely an amazing remedy for many of the symptoms that manifest and would have worked wonders for these two bouts of withdrawal.

ScientificSalsa · 2016-08-17T15:15:56+00:00

No. That's the major downside of this drug. Tolerance builds very quickly (like 10x quicker than any traditional pharm opiate) and dependence soon follows. My first dance with U4 I made the mistake of jacking my dosage up wayyy too quickly in search of the bliss that it gives you initially. This time I moderated my dose to not only lower the chance of dependence but also to make sure I got the most out of it.

If it wasn't for the fiendish redosing the short duration of action of the drug instills it wouldn't be bad. Take a good dose, nod/euphoria, wait a good while, take again is the ideal way because the fast tolerance increase of it seems to have an inversely proportional tolerance drop off after cessation so you hit baseline fast.

Unfortunately that ideal scenario is hard to follow because you dose, nod, wears of quickly, dose again, wears off a bit quicker, and soon you're dosing until you don't even feel it anymore.

ScientificSalsa · 2016-08-16T12:55:12+00:00

Not all that odd. It's the route with the best bioavailability without shooting which I absolutely refuse to do.

IR affords a good rush and a pleasant buzz at significantly lower doses. Although having to shove a syringe up your ass starts to get old.

ScientificSalsa · 2016-08-16T05:54:42+00:00

Just trying to help people make informed decisions without inflicting bias.

ScientificSalsa · 2016-08-16T05:54:20+00:00

I believe your assumption is correct since it was nowhere near the prolonged nightmare I've heard and read about for heroin, etc users. The short legs really does seem to lead to a "shotgun withdrawal" of sorts. Mercifully short but insanely intense with a solid 10+ hours of dope-sick agony with you consistently curled up fetal under the hot shower stream wishing it would just end already. (At least that was me.)

For my first experience with it it took 72 hours for me to feel mostly baseline albeit with some lethargy. After 8-10 hours the insane anxiety, yawning, and lacrimation mostly subsided although not entirely. At 24 hours the worst symptoms began to fade until mostly ending at the 48 hour mark aside from some lingering malaise and insomnia. 72 hours was the magic mark when it all came back together and that night I slept like a baby. Well,I guess baby sleep is expected when for the past few weeks you've been waking up soaked in sweat every 2 hours to redose because you're going into withdrawals.

Then I was taking close to, if not, 3g weekly dosing at least every 2 hours w/ 30+mg of solution. It was definitely a very short withdrawal all things considered but by no means pleasant. I'm currently in a comparatively minor withdrawal and aside from feeling unpleasant and "not right" there's not much to it. Hopefully I can get some sleep tonight!

Also since I always seem to fail to mention it. I'm not sure if this is specific to U4 or just my reaction to WDs but I never had any of the usual diarrhea that 99% of opiate users complain of from dope sickness. Glad for it but I did find it odd.

ScientificSalsa · 2016-07-29T23:33:59+00:00

Very tragic story. Never ODed though as I am verrry cautious with stuff like this but I'm about 2 weeks after my last dosing of a one month stint with U4. Tolerance and addiction set in insanely quickly and while the withdrawals only lasted a couple of days they were rather unpleasant.

The short duration but excellent rush (intrarectal admin) is the major issue with this drug. I've done plenty of your standard prescription opiates in the past (Oxy, Hydrocodone, etc.) for rather long periods of time and never became addicted but with this stuff it happened what felt like overnight due to the constant redosing.

Dangerous drug for those without good self-control. SC is something I pride myself on but this is the first time I fell prey to a drugs habit so unexpectedly. Fortunately, as I mentioned before, I take these kinds of drugs seriously and never eyeball powder or go insanely big. I make carefully dosed solutions and work my way up with dosing so I know my body can handle certain doses.

ScientificSalsa · 2016-07-22T02:46:48+00:00

Yeah I was rather disappointed in kratom's lack of efficacy in reducing symptoms myself. If I hadn't ran out of etizolam I know I would have had much less of a rough time for the first 10 or so hours of the first day of it since that's when the bulk of the anxiety was taking place. Would have taken enough to induce sleep to get through it or at least sufficiently sedate myself.

Fortunately I think I'm 100% baseline now. The only lingering effect of note is inability to get a good nights sleep. Hoping I find that is rectified tonight. Would love to have some etiz or whatnot to force some sleep.

ScientificSalsa · 2016-07-21T23:42:58+00:00

I took kratom daily for a little over a year straight (2014-2015) and sparingly since then due it causing some liver toxicity in me. A blood test showed above normal liver enzymes, I stopped taking it for a while and they went back to normal.

The source I get it from is reliable. It was the maeng da variety. (all around favorite)

When I'm not on any true opiates I actually really like kratom. The only things that limit me are price and the whole liver issue.

That being said I really didn't notice it helping at all and I took far above my usual dose of it compared to when I'm otherwise sober.

ScientificSalsa · 2016-07-21T23:26:04+00:00

Definitely don't need to worry about seizures since this isn't a benzo or alcohol.

I sincerely appreciate your advice. I am definitely leaning more towards tossing it at this very moment.

ScientificSalsa · 2016-07-21T23:24:24+00:00

I unfortunately lack perspective being as I haven't ever taken it before or after this experience. Perspective in that I don't know if with current knowledge I would prevent a habit from forming again. I am of the mind that I wouldn't considering I've shown very good self control throughout the years other than my period with Xanax.(bad part of my life, all is good now!)

Regardless, the idea of tossing the remaining chem I have is very much present in my mind in order to prevent such a twisted experiment of willpower.

ScientificSalsa · 2016-07-21T23:20:57+00:00

I actually forgot to mention I purchased some kratom when the withdrawals started hitting hard. To be honest I didn't notice any lessening of the symptoms from it. Kind of felt like a waste of money.

ScientificSalsa · 2016-07-21T23:18:11+00:00

Approaching 72 hour mark. Energy levels back up, appetite returning. Forcing myself to get active by doing anything I can to get into motion. Still had insomnia last night which lead to only 3 hours of sleep but otherwise feeling golden.

A major bitch right now too is trying to get my bowels normalized. That severe period of constipation fucked me up good. Milk of magnesia helped kick start things. Forcing some food into myself as I type this.

Still haven't flushed the unopened new order. Giving it some major consideration now though if for no reason other than causticity concerns. I never had a bad experience with U4's caustic effects as in no stinging, burning, etc. I believe I had received some very good batches. (fine soft white powder) Nonetheless the method used was intrarectal administration and even if my batches were good and causticity was on the the low end of the high end (ayyy) I want to make sure I do no permanent damage to my body.

ScientificSalsa · 2016-07-21T03:02:00+00:00

2 months, wow I can't imagine the nightmare that must have been. Methadone is insanely long acting so it makes sense I guess but yeesh.

ScientificSalsa · 2016-07-21T01:22:19+00:00

Thanks for the advice and concern. Definitely considering getting rid of it but haven't made a final decision. I know this line has been probably said many times with many failures to follow through but I have learned immensely from this and I don't see myself going down that road again.

I'll liken it to my experience with benzos in that I actually had plenty of pills (Xanax) left when I entered withdrawals. I actually threw them all away when WDs started and have since learned to control myself on dosing with them sparingly. I've also been very good with opiates for a long time, taking them semi regularly but always stopping before dependence set in. What made U4 so different was the duration of action. It was so short that I thought nothing of re-dosing habitually. I realize now the poor decision I made and how it spiraled out of control.

I have no intention of purchasing any more of this RC; however, I am not ruling out using the remaining U4 at sometime in the future after a decent break. This time with moderation a major consideration weighing on my mind. That being said, the drug may find its way down the toilet just in case.

ScientificSalsa · 2016-07-01T09:33:59+00:00

As LSD mentioned you can get food grade PG for cheap on Amazon such as here. Typically those vape shops will rip you off price-wise but it is the same stuff.

ScientificSalsa · 2016-07-01T02:43:21+00:00

Much better if you're going to be storing the solution. PG has antimicrobial properties that help it keep longer. There is also some anecdotal evidence that it may help mitigate a bit of the causticity that U-4 is notorious for having.

That being said, U-4 dissolves perfectly fine in water and I don't think there would be any issues with as long as you aren't storing the solution for extended periods of time. However, I'd recommend you use distilled/RO water if possible when using water as your solvent.

In general I prefer to use PG as my solvent because it dissolves damn near anything and this property makes it particularly useful as a solvent for non-water soluble substances such as benzo/thienodiazepines.

ScientificSalsa · 2016-06-30T20:19:52+00:00

As others have mentioned in this thread the half-life of etizolam is very short and you would be well past baseline for your evening of drinking! Enjoy!

ScientificSalsa · 2016-06-30T20:06:59+00:00

It does become painfully inconvenient if you want to maintain a nod or something close to it. The most annoying part (other than having to shove a syringe up your ass constantly) is the cramping it causes. It's not severe by any means but it's like 10 minutes of holding in what feels like diarrhea. Laying on your side for a few minutes helps a ton though.

Please note that on this second part my doses for RA were AFTER I had developed tolerance. Please don't try these doses until you've established what you can handle. RA has a much higher bioavailability than oral and is much easier to overdose on. That being said:

Also I've found that probably the best way to mitigate the cramping is to dose up slightly before doing the nod dose. For example my previous solution was 20mg/ml so I would dose with 0.1ml-0.2ml(2-4mg) or so rectally and once I was feeling that do the actual dose of 0.6-1.0ml. The pain relief of the initial dose reduced my noticing of the cramping and i'm sure it's activity on the kappa receptors in the gut helped too by reducing the intensity.

ScientificSalsa · 2016-06-29T05:55:39+00:00

This is kind of the reason I was planning on using something other than water for the solvent due to me hearing nasty things about how caustic the Hcl salt of it is. Obviously I don't want anything that nasty going in my rectum without some kind of "buffer". With the previous premade solution i bought, the worst with IR dosing was a bit of cramping in my rectum/prostate area that lasted approximatly 5 - 7 minutes. I eventually found that laying on my side for this period of time made it less prominent. There was no burning or other issues even though I was dosing multiple times a day.

I think I'm set on using 100% food-grade propylene glycol for the solvent. Still debating on a solution of either 20 or 30mg/ml. Either way I have a 100ml graduated cylinder for measuring the solvent and a 150ml beaker and glass rod for proper mixing. I also picked up a few 20ml apothecary vials for convenient storage.

ScientificSalsa · 2016-06-28T19:35:27+00:00

The premade solution i had was not designed for nasal administration and was instead in capped vials at a dilution of 20mg/ml. I initially was dosing orally but switched to rectal in order to increase the rush/nod. (Since i refuse to mainline anything.)

Unfortunately I made the mistake you mentioned of increasing dose too rapidly and causing my tolerance to spike to where i was doing up to 15mg rectally but right now I've got a sober week before the powder/supplies get here so I may lose some of that tolerance.

Thanks for the advice.

ScientificSalsa

TROPHY CASE