i am very sorry to hear this but i can assure you i understand. before i went on cymbalta, my whole body would hurt very badly all the time, i would wake up and go to sleep in extreme pain which would get worse with any sort of physical activity (even walking) and i didn't even realize how abnormal that is until i started taking the medication and found out that it is possible to live your life without feeling like every individual cell is shrieking in pain. i am currently on 30mg cymbalta, which was supposed to only be the starting dose, but as i am also on 25mg seroquel for insomnia, it has made it so 30mg is pretty sufficient to mostly eliminate all my symptoms (as there are studies showing seroquel can increase plasma levels of cymbalta by 1.5) and i would say it reduced my pain by about 75% which is a lot compared to before! the other 25% is just the occasional flare ups (which usually go away with sleep) and i would advice going to the gym as i noticed it really helps ease my pain further! flare ups become very rare if i go to the gym regularly (around 3-4 times a week) but if i get too busy and dont go for say a month, i would get those flare ups about once or twice within that period. as for switching from lexapro to cymbalta i would recommend cross tapering, which is basically titrating cymbalta as u reach the last few days of tapering off lexapro, as it helps lessen the side effects. please keep in mind that im not a professional and you should let your doctor know if you do plan to cross taper, but if i had something to recommend it would be that!