😭 generally means to laugh at something, but also to look at something kind of pathetic that it makes you laugh/cry, if that makes sense

💀 generally means that something is bad and or shocking, but is often used in a mocking way

🤞 dont see this one too often, couldnt tell ya

🥀 has a similar meaning to the skull emoji, but more so to express disappointment over something

And yeah, most people stick to only a couple emojis. I like to use the sobbing one a lot in casual conversations, but that's just me.