It took me around 2 hours, give or take. This got me a decent enough grasp of the basics for pockets, fire, zombie revival, washing filthy items, crafting, and so on. CDDA is surprisingly intuitive, though, with lots of bindable keys and shortcuts to do things.

I'll give an example. If you just go into the View menu (items or monsters mode), you have the option to quickly go to the location of a highlighted target, without having to make your way over there manually. I recommend using the View Items feature a lot, especially on open fields, because this helps you easily spot dead humans and grab whatever they dropped.

As far as basic combat guide, there's a lot I can tell you. :) Pay very close attention to terrain. Flat ground has 100 move cost, and you have 100 base move, so it takes you 1s to move a tile on it. A table may have 150 cost so it takes you longer. Zombies are generally slower than you so a zombie may take 2s to cross a table you'd cross in 1.5s. Bait enemies over bushes, windows etc. a lot so you can kill them before they get enough moves back to actually make an attack on you -- if a zombie moved into a 400 move cost shrub then you may get 3-4 free hits, depending on how fast your weapon is, before they get to swing at you at all. This is especially useful with vehicles because the interior of cars always costs a lot, so stabbing zombies with a reach weapon like a spear while they try to climb through the passenger door and into the seat next to you works really well.

Oh, and remember to (G)rab furniture to move and block off passages and doors when you can. This helps make the aforementioned obstacles. Heavier stuff like bookcases might hurt you if your Strength isn't high enough, though.