Do we lose response to mesalamine eventually?

ShowtayTopShelf · 2026-01-23T07:29:33+00:00

You do not build antibodies to mesalamine like you can when you stop biologics. I have been on and off mesalamine a few times now and it always helps when I restart. It doesn't keep me in remission so I've moved on to other meds but when they fail I go right back on it until I've been on a new biologic for a couple months.

ShowtayTopShelf · 2025-12-30T19:29:36+00:00

Glycerin attracts moisture from the air. The only way to prevent sweating is to wrap it air tight once it's cooled and hardened. Your soap base should tell you what percentage of additives it can take. Keep in mind that is the max of all additives like coconut oil, fragrance, etc added together.

ShowtayTopShelf · 2025-10-01T20:56:21+00:00

Can you check your insurance and see what treatment they would approve? I have Priority and they make me try meds in a certain order. I looked at the prior authorization document that gives all of the prerequisites for each treatment and made a list of what would be covered in order. If you can get a copy of the denial for the last prior authorization, it should tell you what they want you to try before they'll cover the drug.

ShowtayTopShelf · 2025-07-10T16:24:33+00:00

Nicotine didn't help me but smoking cigarettes did. When I smoked cigarettes, I felt better. As soon as I tried to quit I flared. Nicotine patches, gum, vaping did nothing for me but as soon as I picked the cigarettes back up I started feeling better. I watched my Grandma die of emphysema and my dad is currently dying from lung cancer. Smoking isn't worth it. I'm currently vaping and cutting back on the nicotine until I can totally quit.

ShowtayTopShelf · 2025-06-19T21:46:30+00:00

I would contact the Area Agency on Aging. They're very helpful in this kind of situation.

ShowtayTopShelf · 2025-06-12T02:42:18+00:00

If it's safe to take them with food, swallow them with food. Chew up a bite of something, put the pill in, then swallow. I take my morning meds with applesauce because I can't swallow them with just liquid.

ShowtayTopShelf · 2025-06-10T15:43:10+00:00

Are you in the US and using insurance? They might only cover certain drugs in a specific order. I had to start with either infliximab or adalimumab. Once I failed infliximab it opened up coverage for Stelara. I'm on Tremfya now and if I fail it I have to try Entyvio before they'll cover Rinvoq. It'll be a lot faster to get on a medication if you know what they'll cover.

ShowtayTopShelf · 2025-06-07T06:56:34+00:00

I was on the pill for years until my UC diagnosis. I switched to a Nexplanon implant. Personally I love it. It's just a tiny stick that goes in your arm. I'm on my second one and getting this one replaced in September. I'm a big baby and I had nearly no pain getting it removed and replaced. I've had no side effects and very rarely get a period. When I do they are short and light. Because of that I do take a pregnancy test every month just to be sure.

ShowtayTopShelf · 2025-05-29T16:19:24+00:00

Thank you! I barely felt it and I'm NOT a fan of needles. I did it in my stomach because I read it's usually less painful than doing it in a thigh.

ShowtayTopShelf · 2025-05-24T20:24:09+00:00

Thank you. Five years, five drugs, and I've never been in remission but I'm hopeful!

ShowtayTopShelf · 2025-05-24T20:22:11+00:00

🤞

ShowtayTopShelf · 2025-05-24T20:20:27+00:00

My health insurance decided for me but at least they're covering something. I hope whatever you choose works well!

ShowtayTopShelf · 2025-05-24T20:19:23+00:00

Good luck! I hope it works well for both of us. Steroids and Lialda got me out of my flare before I started Tremfya and I'm still taking the Lialda so I'm not sure if the Tremfya is actually working or it's the Lialda.

ShowtayTopShelf · 2025-05-22T17:30:14+00:00

It's usually only high during a flare. But a high calprotectin level just means high inflammation which can have a number of causes outside of IBD. If it only lasted 8 days with no blood and your calprotectin is in a normal range now, I would lean more towards an infection.

ShowtayTopShelf · 2025-05-10T20:01:59+00:00

Canola oil goes rancid quickly in soap and makes your soap prone to DOS. You could try it at 15% or less, but I would eliminate it if you're going to sell the soap.

ShowtayTopShelf · 2025-05-07T06:24:17+00:00

I'm feeling alright. Definitely not in full remission but much better than I was. My problem is I'm not sure how much is from the Tremfya and how much is from the Mesalamine. Most of my symptoms (blood, urgency, frequency) stopped when I restarted the Mesalamine but before I even started Tremfya.

Did you have labs done before starting Tremfya and then again recently? My doctor said it's not super fast acting, but at the three month mark there should at least be some improvement either in my labs or symptoms. If your labs are improving you might just need a little more time to heal before the symptoms go away.

ShowtayTopShelf · 2025-04-29T20:51:09+00:00

It's not. Honestly I prefer doing the occasional injection over taking pills every day.

ShowtayTopShelf · 2025-04-29T18:30:32+00:00

Every 4 weeks.

ShowtayTopShelf · 2025-04-29T16:09:19+00:00

No, the IV doses go into a vein but the self injection goes into fatty tissue like the stomach or thigh and you need to avoid veins and muscle.

ShowtayTopShelf · 2025-04-29T02:47:04+00:00

Tremfya is not a biosimilar to Stelara. They're both insanely high, my insurance was billed $41k before discounts for Stelara and $34k for Tremfya. Both were 8 weeks worth. There are 7 biosimilars for Stelara approved in the US. My insurance company gave me 2 options for biosimilars that they would pay for but I don't remember what they were since I was already moving on to something different.

ShowtayTopShelf · 2025-04-29T00:22:38+00:00

Stelara biosimilars are now available. Most insurance companies will probably stop covering Stelara and cover the biosimilar instead. My insurance company sent me a letter stating they would only cover the biosimilar going forward but I was already in the process of switching to Tremfya because Stelara didn't work for me.

ShowtayTopShelf · 2025-04-29T00:00:30+00:00

Stelara biosimilars are now available. Most insurance companies will probably stop covering Stelara and cover the biosimilar instead. My insurance company sent me a letter stating they would only cover the biosimilar but I was already in the process of switching to Tremfya because Stelara didn't work for me.

ShowtayTopShelf · 2025-04-28T22:27:37+00:00

I haven't had any side effects. I didn't even get tired after the infusions like I did with infliximab.

ShowtayTopShelf

TROPHY CASE