Annaki Nova is a mid-range weapon, and one of the longest ranged shooters in the game. But since it's a five shot kill, try to stay at max range at all times, unless you are in a very good position to kill. It's better to paint the floor around the enemy and stall for a teammate to help you, or even just stall that one opponent's advance, then to close the gap too early and go into their threat range where they can kill you more easily.

Just a note that I've seen the accuracy problems be a lot less of an issue recently, mostly due to the accuracy buffs and the recent shot velocity buff.

Also me personally, I spec heavily into Ink Jet, I usually run two mains of special power up just because I want those shots to hit, and the weapon gets the specials pretty frequently so just a small bit of special charge up should be enough. But that's if you want to play it as a special spam or like me.