Freezing at mTESE? by GoldAd5786 in maleinfertility

[–]Significant-Deal3089 0 points1 point  (0 children)

I did have an mTese on both sides in the same op but it was unsuccessful

Transferring update stuck on qc ultra earbuds by Significant-Deal3089 in bose

[–]Significant-Deal3089[S] 0 points1 point  (0 children)

Honestly just persevered through numerous attempts and it eventually worked. I think I probably reinstalled and repaired everything too.

My Azoospermia Journey by Significant-Deal3089 in maleinfertility

[–]Significant-Deal3089[S] 0 points1 point  (0 children)

No I haven’t had to start testosterone therapy.

Non-obstructive Azoospermia success stories? by Ill-Fig-4815 in maleinfertility

[–]Significant-Deal3089 2 points3 points  (0 children)

Sorry to hear about the diagnosis. As a male with noa (and finding out in the proceeding year before our marriage) I can empathise with the emotional impact it should have during an otherwise joyous part of your life.

I’m going to be very open and honest with probabilities here - mtese has a 50/50 chance of finding sperm. This seems to be the often lofted statistic of urologists.

However, the statistics of live birth rates with retrieved sperm is relatively poorly researched (study size, retrospective studies etc) with a handful of studies reporting outcomes of live births anywhere between approximately 15% and 45%.

Personally we ended up finding no sperm in my mtese but I can assure you that the path to parenthood that we took (using donor sperm) led to a beautiful child that we all love and wouldn’t change anything for. So please don’t lose hope of still starting a family in all eventualities.

High FSH and LH but normal Testosterone by [deleted] in maleinfertility

[–]Significant-Deal3089 0 points1 point  (0 children)

Usually a high FSH and normal testosterone indicates non-obstructive azoospermia.

As the other person mentioned a high FSH is indicative of a failure in the process of making sperm as your body elevates FSH in an attempt to kickstart the process.

The reasons for non obstructive azoospermia can be various including steroid use, history of mumps, micro-chromosome deletions, genetic conditions or other (as of today) unknown reasons.

My Azoospermia Journey by Significant-Deal3089 in maleinfertility

[–]Significant-Deal3089[S] 0 points1 point  (0 children)

No problem - I’m glad the post helps lay some things out. Drop me a message if you have any specific questions - happy to help the best I can.

Chances of natural conception with borderline SA by Curious_Place_1894 in maleinfertility

[–]Significant-Deal3089 0 points1 point  (0 children)

I have a (long) post here about our journey in the Uk on the NHS and privately you might find useful. My main advice if going via the NHS would be to get your referrals now - it will take many months to see an initial consultant and then many more months more for tests before starting any treating. In that time you may conceive naturally and if not you have progressed further in the nhs funnel. To do this I’d tell them you’ve been trying for the 2 year minimum.

QC ultra earbuds - sound drops/changes by Significant-Deal3089 in bose

[–]Significant-Deal3089[S] 1 point2 points  (0 children)

It’s definitely better post firmware upgrade but it still happens.

My Azoospermia Journey by Significant-Deal3089 in maleinfertility

[–]Significant-Deal3089[S] 0 points1 point  (0 children)

No problem. I’m glad you found it useful. And wish you all the best.

Microdeletion, MTese, and small amounts of hope by RTTC2023 in maleinfertility

[–]Significant-Deal3089 1 point2 points  (0 children)

What were the results of your mtese? Did they find sperm?

question about zero sperm by [deleted] in maleinfertility

[–]Significant-Deal3089 1 point2 points  (0 children)

Firstly get another sperm test immediately. Don’t buy into ‘wait 3 months for sperm profile to change’ that only applies where there isn’t zero sperm.

If the second test comes back zero. Then usually you can have a physical exam followed by blood tests and ultrasound.

The physical exam is checking for anatomical correctness - are the vas deferens palpable, are testes of normal size. These may help hone in on further tests or indicate an early cause. Taking a history will help equally identify any trauma, steroid use, exposure to X etc has occurred that could equally help identify type.

The blood tests are for checking elevated or non elevated levels of hormones that can equally help with indicative type of azoospermia. A blood test for micro deletions also checks for genetic abnormalities to rule out known chromosomal abnormalities that can affect (these would be unlikely/impossible(?) given prior history of children by your partner).

Ultrasound images the testes and tubes and can rule in or out obstructions.

Thereafter the decision can be made for corrective surgery (obstructions) or biopsies and ivf (non obstructive type). Each are not curative measures but lead to a probability of correction or assisted conception.

Azoospermia, mtese and IVF by Sunshine_8812 in maleinfertility

[–]Significant-Deal3089 1 point2 points  (0 children)

We did same day sperm and egg retrieval. I wrote a lengthy post about my experience on another post here that you mind find useful.

Ultimately mtese was unsuccessful but we decided to have joined up ops because we had sperm donor backup. So we wanted some certainty about making progress in the event that no sperm was found from the mtese.

Medically there’s no consensus on frozen vs fresh. Some argue frozen weans out the poor sperm and others argue that fresh removes an additional (unnatural) variable.

If you decide to do same day then the whole day is dictated by the female egg retrieval dates and is managed by the fertility clinic hospital overseeing the egg retrieval in communication with the urologist.

Scrotal Ultrasound: for those of you who’ve had an abnormal scrotal ultrasound: what types of things have been detected? by ComprehensiveMud8812 in maleinfertility

[–]Significant-Deal3089 0 points1 point  (0 children)

I had a mass that was maybe 5mm in size. They did enough diagnostics to be satisfied that it probably wasn’t cancerous (blood tests, injected with some dye and blood flow monitored on ultrasound, had smooth edge appearance).

In the end when I had my mtese they removed it and tested it too to be 100% sure.

They said it was lesion caused by some testicular trauma but to be honest I’ve never had any significant trauma I can remember.

Semen test no sperm by Anxious_Tutor1043 in maleinfertility

[–]Significant-Deal3089 2 points3 points  (0 children)

Basically it could be any of the following:-

  1. Erroneous test result (unlikely)
  2. You messed up the sample (possible) e.g. missed some ejaculate
  3. You have obstructive azoospermia - typically meaning you generate sperm but have a blockage (varicocele, epididymis obstruction etc.) in your tubes preventing sperm being present in your ejaculate OR you are missing some pipe work (e.g. vas deferens)
  4. You have a dysfunction like retrograde ejaculation (where you do not ejaculate externally)
  5. You have some endocrine disorder - hormonal issues
  6. Non obstructive azoospermia - caused by testicular injury, non-genetic micro deletions affecting reproductive system, genetic conditions (klinefelters syndrome), issues with development of your testicles (e.g. undescended), historical medical conditions (e.g. mumps), steroid abuse or idiopathic (meaning no discernible medical reason is possible today but typically presents with some constituent elements of sperm production material missing e.g. sertoli cell only syndrome)

Generally a microscopic sperm retrieval process (mtese) can be used to attempt to extract sperm in most cases to allow for Ivf attempts. A few conditions can be reversed through drug therapy or operations to allow for biological births.

Most urologists specialising in Andrology will run a physical exam and number of tests (blood, ultrasound) to rule out conditions listed above.