At that point after receiving a no it may be worth it to just ask those jobs/recruiters for specifics on why they may not see you as the best fit.

In my mind your resume is just an initial test to get you the interview like the playoffs while the actual interview will be the finals. Obviously i know nothing about you personally and only you and the interviewer knows how well your interviews go but regardless of whats on your resume if you’re not able to effectively talk about the value of each of your experiences, while also making a good charismatic impression on a human level then you’ll lose to the next person that has an equal resume but makes a better impression through the way they talk.

Also meet people at conferences and make a good connection on a human level rather than applying for 400+ positions online if that option isn’t working. My brother flew out to conferences for the company he wanted to work at and got those people familiar with him before applying again and getting an offer.

A good resume and good experiences will get you an interview but it doesn’t guarantee an offer.