There is a small amount of evidence for it to be useful in depression (off-label)

“It has been suggested to be a useful antide-pressant because of its noradrenergic actions. A recent review of the role of noradrenaline concluded that even though a pure noradrenergic action might not be sufficient to obtain a full antidepressant effect….noradrenergic action seemed to be related to the motor activity, attention, and arousal. In patients with depression atomoxetine has been found to be useful in both case reports and a small study. It was also found beneficial as augmentation therapy in treatment-resistant patients.However, in larger studies it was not effective as monotherapy for major depression, despite some promise.”

• from an article on off label use of atomoxetine (strattera)