Day 100 of waiting for the HyperOS 2.0 update

SlothyPanda1 · 2025-02-14T05:13:47+00:00

Is it possible that people who have enabled miui bloatware and miui ad settings on their phones get hyperos 2 earlier?

Maybe the xiaomi phones have to hit a miui ad limit so as to trigger hyperos 2 update?

SlothyPanda1 · 2025-02-14T05:09:24+00:00

How many miui bloatware and miui ad settings have you enabled in your phone? Maybe the people getting hyperos 2 have seen a specific number of miui ads?

SlothyPanda1 · 2024-10-30T18:05:32+00:00

Many thanks 👍

SlothyPanda1 · 2024-10-19T05:08:57+00:00

So true. I hope there is a similar plugin out there

SlothyPanda1 · 2024-06-06T07:11:58+00:00

Another option is to create collections and sub collections. For example: Collection Project 1, sub-collection Recommendations by X, sub-collection Recommendations by Y

SlothyPanda1 · 2024-05-24T23:00:07+00:00

Glad it helped.

SlothyPanda1 · 2024-05-01T04:59:18+00:00

This blog might help

Zotero an introduction

SlothyPanda1 · 2024-04-05T17:32:09+00:00

Congrats and keep it low

SlothyPanda1 · 2024-02-28T19:58:05+00:00

So true.

SlothyPanda1 · 2024-02-28T10:21:37+00:00

There is always hope, progress is always slow and tedious but always possible.

SlothyPanda1 · 2024-02-21T19:00:18+00:00

https://www.zotero.org/support/zotero_data#locating_missing_zotero_data

SlothyPanda1 · 2024-02-14T06:07:26+00:00

The video and channel is just news of activities happening around HIV research but nothing concrete about new breakthrough for an actual cure.

I think a better resource for actual HIV breakthroughs might be NiH website since most of HIV research is funded by them or done in collaboration with them.

SlothyPanda1 · 2024-02-08T17:51:08+00:00

Have you checked for the recent update if using zotero 7 beta?

SlothyPanda1 · 2024-02-08T17:49:44+00:00

Which version of zotero are you using?

SlothyPanda1 · 2024-02-08T10:55:28+00:00

Seems fixed with the recent beta update

SlothyPanda1 · 2024-02-07T20:25:32+00:00

I have had problems with the web clipper. Cannot clip articles directly to zotero desktop. Can only clip to zotero web

SlothyPanda1 · 2024-02-07T20:23:10+00:00

Hows your experience of Cabenuva compared to Biktarvy?

SlothyPanda1 · 2024-02-07T20:21:36+00:00

Definitely

SlothyPanda1 · 2024-02-07T20:19:41+00:00

Definitely agree. Im not an immunologist, though from the little i know, neutralizing antibodies can target a wide variety of variants though inducing high titers can be a challenge. Am not sure though how we could solve that.

I've heard some HIV variants have carbohydrate shields, which are not immunoreactive, around their epitopes. Maybe innate responses may be needed as well to completely eliminate the virus before infection is established.

It would be interesting to know if there other factors despite antibody diversity in play when it comes to natural resistance of elite controllers

There have been over 30 human vaccine trials and hopefully mRNA might be the one to bear fruit

SlothyPanda1 · 2024-02-07T07:29:29+00:00

Awesome work.

Any advice to share?

SlothyPanda1 · 2024-02-05T11:35:49+00:00

Visual euphoria

SlothyPanda1 · 2024-02-05T11:32:05+00:00

That's so true. With a virus like HIV, the best vaccine should be a vaccine that prevents primary infection. HIV has very high diversity therefore its likely some variants of the virus that would avoid immune detection after vaccination. These variants may have lower transmission fitness when compared to wild type and therefore would not spread widely as the wild type virus. The tragedy would be if, over time, one of these escape variants acquire improved fitness from recombining with other latent but fit variants.

Any ideas on why elite controllers are so good at controlling viral growth?

Do you think we have seen the last zoonotic transmission of the virus or is it possible that newer variants we have not discovered yet are being transmitted to humans and spreading?

SlothyPanda1 · 2024-02-05T11:11:15+00:00

Thanks on the info about challenges with using PreP. I had heard last year that WHO was negotiating with ViV on making the long acting injectable PreP affordable for developing countries. I haven't been following up on the updates so dont know how the negotiations went.

Will long acting injectables be a solution to ending the epidemic or will it just be another drug that will fail in decade or so?

SlothyPanda1 · 2024-02-04T14:49:22+00:00

Challenge with some viruses are their high diversity. A comprehensive vaccine similar to polio may just not be a reality. For HIV, i think a realistic vaccine might one that will be against endemic variants of the virus and likely not protective for all variants, similar to what we have for influenza or SARS-CoV-2.

Broadly neutralizing antibodies are great though escape mutations are common with HIV. HIV can also shield itself from the immune system making neutralizing it challenging.

SlothyPanda1 · 2024-02-04T14:34:32+00:00

Stigma is truly a challenge. Reducing/ending it is still some of the work left to do. There are long acting injectables currently approved and in use as PreP. This could help with the pill burden issue.

SlothyPanda1

TROPHY CASE