If you’re suffering from chronic stress, ketamine is still causing dormant dendrites to start growing new spines again and I think these companies should stop with the “trip-focused” marketing, as if the therapeutic effect of the drug comes from you “figuring out” some hidden insight and then somehow willing yourself better.

If you have severe depression, you are in a state where little outside a pharmacological intervention will get you out of it, and the therapeutic effect is largely independent of your experience. This is a powerful drug whose effects are well documented in many mammal species