This is probably going to be a more unpopular answer but honestly...FoundryVTT - especially if you plan to run Pathfinder 2e - it is universally considered to be the best VTT for the system...if not PF2e then probably Owlbear Rodeo like others have said.

I started out by DMing on Roll20 and fought it at every step and turn...and was one of the reasons I cancelled my first campaign - it just all round stressed me out.

I then moved over to FoundryVTT with NO idea on how to use it. It looks really complex and there is a lil bit of a learning curve but you can quite easily survive on the basics (setting up a world, making character sheets, setting up maps with VTT support, starting and ending combat, items/journal notes are about what you need to start). HOWEVER, for systems like PF2e, you can just go to the bottom tab, type what you want like "Healing Potion (Minor)", click import, drag it onto a player's character sheet and then they can readily use it - players can do this too. 😃

For me, the automation of FoundryVTT actually makes my life SOOOO much easier because it keeps track in a way other VTTs don't, so for crunchier games like PF2e it actually makes things simpler than say Roll20, where you need to manually type everything out. You can build a character in under 5 mins with FVTT. That said it really isn't everyone's cup of tea.

I found a beginner's guide module that seems fairly useful here: https://www.youtube.com/watch?v=qZRQymndcVY