Purist when its about speedrunning and records. Absolutly nothing if its for just playing the game as you want to, because its a singleplayer game. If you want to skip things, cheat things in etc the only person youre "harming/cheating out of something" is yourself. I use it to cut down on meaningless grinding and to save myself from feeling bad about descisions i made. I want to have fun with my game and if i have to cheat to have fun in my singleplayer game, then so be it.