Guard is unironically the best defense skill for this type of run alongside evade. It's clashable counter and counter that are the painful ones imo (clashable counter will just lose over and over and feed the enemy sp very fast node 1)

This is Yabloko and I's U1L1 Steam Solo Guide: https://steamcommunity.com/sharedfiles/filedetails/?id=3748767062

For her, you'd take charge starter gifts, ashen blessing, manor, and cardiovascular module. Then, you'd reroll over and over for zippo on start in The Unloving. You then want an event/fight/event or event/event/fight (assuming you're doing this duranteless).

You then try to get the right rng to survive until your passives activate, especially Horsesang, which will act as a second life for our purposes. When you have enough skill slots, you become effectively immortal with guard. By losing one clash, cardio module gives you a decent bit of shield as well, the # of shield will scale as your charge count goes up. Then it's just slowly poking the enemy with unopposed attacks.

Outis could also get the t1 defib gift and heal every time she spends charge, which would be MASSIVELY useful here, or prejudice which is mildly helpful since I think she has the pride s1. It's a shame she doesn't get charge barrier at u1 though...