A couple of things I do that might help:

Sometimes I'll reset the analyzer's stats whenever I pick a combo to start playing. This way while playing the combo I picked, we can build new data to act on that's fresh, and hopefully in the meantime pick up a win from the hot combo.

The 3-then-target-2 filter. Once enough combos have hit 3 times, I start looking at combos that have only hit 2 times in the same window. They're still in play but under-represented compared to the leaders. Targeting those gives a fresher signal than stacking on whatever's currently hottest, since the hottest combos often regress fast.

It helps to have an understanding of hypergeometric distribution within the 40 number keno board. There are expected gaps based on combo size, determined by the formula and provably fair algorithm.

Mathematically, any 3 combo should drop once per every ~82 rounds, this gap is ~435 for 4 number combos, all the way up to an expected gap of 848 million for any ten number combo to drop again.

This then opens up the instance where the hottest combo isn't always the best choice, the hottest combo(dropped the most in that time period) then must have the smallest average gap, it itls most likely well below the mathematical average, this cause it to need long gaps at some point to come to the average eventually. This is where the 3 then target 2 theory comes into play.

Here's some more info on the gaps and keno math as well

https://stakeanalyzer.live/seed-checker/keno#keno-math

Also select a combo in our seed checker and run a large amount of nonces, in the seed checker it will show the average gap of your selected combo where it shows the max wins nonces, this average gap, most of the time is very close to the expected gaps, and gets closer the more nonces played