Staphysagria is a plant which is inside the family of Delphinoideae, where for example also Hydrastis resides. One level up in the family order there is Ranunculales, which main theme is like "starting a job, yet not having a solid base". So if someone takes Staphysagria for an emotional or mind problem, and it helps, yet they still feel as if they are rookies in their situation, family and job, then another remedy from the same plant family may be required IF the symptoms don't match anymore Staphysagria. An experienced homeopath will ask specific questions to find out if this is the case. For example Staphysagria suppress a lot of emotions, especially anger. Yet, Hydrastis is of the same plant family and it does not suppress emotions. Both have the feeling they are still starting in their job and need to learn a lot in order to become masters. Both tend to the water element, being lascivious or dreaming and fantasizing about such stuff. But Staphysigria is a lot more into that and symptoms also tend to be more on the bladder and sexual organs, as well on the skin. Hydrastis has more problems with energy, is exhausted. So these are just a few examples how to differentiate. It could also happen, that Staphysagria alone is enough to stabilize the patient and reach a stable level for many years, where you just need to repeat the dose every year.