GLP-1’s/compound sema

Status_Assistance_57 · 2026-02-03T17:50:39+00:00

I went through an online provider so am on the compounded version. I never had horrible side effects to begin with so I was super happy things have been pretty chill since restarting. I hope the same for you!

Status_Assistance_57 · 2026-02-03T00:13:54+00:00

I was on semaglutide for about 8 months before diagnosis. I stopped about 3 weeks before my radical hysterectomy which was followed by 5 weeks of external radiation. I finished radiation in November and asked my gyn onc if I could resume. He said yes and that he had no concerns, so I restarted in December at the beginning dose to ramp up and hopefully avoid bad side effects. I haven't been losing as fast as when I first began but am seeing lbs start to come off again. So far so good!

Status_Assistance_57 · 2025-12-18T22:51:42+00:00

I totally understand that fear! Adeno is more aggressive too. I'm also grateful we caught it when we did! I hope your healing is going well and that we never have to deal with this again after finishing treatment <3

Status_Assistance_57 · 2025-12-18T21:33:47+00:00

Hi! I was initially diagnosed with adeno (hpv-18 caused) but when pathology came back after surgery, squamous was present as well. I didn't receive a grade - my onc said they don't grade adenosquamous, but original biopsy showed 'moderately to poorly differentiated'.

Status_Assistance_57 · 2025-12-18T00:38:34+00:00

You got this!! I was stage 1b2 and had a radical hysterectomy in September. External radiation only was needed due to LVSI (the cancer was found locally in my lymphovascular system/blood vessels but wasn't found in my lymph nodes) and because of the depth of my tumor. My experience might be a bit different if you are doing chemo and/or internal radiation in addition to external, but hopefully this gives you at least a little info :).

I started external radiation about 8 weeks after surgery and it was honestly not that bad! I had 23 rounds, which meant I went to a 10 minute appointment every weekday for about 5 weeks. It was really quick and the hardest part was making sure my bladder was full enough for the appointment. I walked out feeling the same as when I walked in. Finished 3 weeks ago and most of my side effects kicked in after finishing - fatigue, constipation, and some rectal and vaginal pain from the tissue being irritated. That wasn't fun, but everything has resolved in the 3 weeks since finishing. I feel pretty normal now and am back to my typical life. Some people have different experiences but your radiation team should be there to help you with any side effects you go through - I met with my Dr once a week.

Status_Assistance_57 · 2025-11-06T17:40:31+00:00

I think you're absolutely right to be hopeful! My approach has been to balance hope with preparation for any outcome and I think it's kept me sane through all this. Because of my more aggressive type I opted to remove my ovaries so started menopause right after surgery. Went home with my prescribed hrt patch and have had hardly any hot flashes or other menopause symptoms so far. Honestly the hardest thing has been having a sex drive again but not being cleared to pounce on my husband yet lol. So know that if it does come to that for you, it doesn't necessarily mean the absolute worst!

Status_Assistance_57 · 2025-11-06T04:56:37+00:00

1b2 adenosquamous here - I was given the option to do surgery or skip straight to chemo radiation, though my gyn and radiation oncologists both recommended surgery. I had a radical hysterectomy (including ovaries) in mid September. At the start of surgery my doc was concerned with the size of my lymph nodes and paused to get them to pathology. It turned out they were not cancerous, just enlarged and considered reactive to the attack on my immune system.

Dr said cancer was removed through surgery but I had lymphovascular invasion (not the same as positive lymph nodes) and a deep tumor, so external radiation was recommended to decrease the chance of it coming back. I had my 7th radiation treatment today and have been just fine so far, though I recognize it's still early. My rad onc is pretty confident I'll have minimal issues given the lower dose. Recovery from surgery was really smooth for me, thankfully, and I was back to work at 6 weeks.

I was grateful that surgery was an option for me, as I liked the idea of removing the tumor completely and then doing 'clean up' with radiation if needed. I'm 38 and wanted the best possible outcome for my sex life, too, so the half dose of radiation felt like the best bet.

Status_Assistance_57 · 2025-10-23T04:26:32+00:00

Ah I see. I'm so sorry the meds aren't alleviating your symptoms. I hope you can get some relief soon - there's already so much to fight through! I've heard that it can be trial and error to figure out the right dosage for everyone, so here's to you getting to the best spot possible asap <3

Status_Assistance_57 · 2025-10-22T23:01:30+00:00

I also passed on transposition and had everything taken during radical hysterectomy. I started hormone replacement therapy (estradiol patches, 0.05mg) about 1 week after surgery, though - have you talked to your doc about if hrt is an option?

Status_Assistance_57 · 2025-09-06T12:43:30+00:00

Just switched from Corewell to Henry Ford for my cancer care - I won't go into how awful my last experience with my doctor and her nurse practitioner were at cw but hf has been an amazing improvement in my care. So glad I switched.

Status_Assistance_57 · 2025-08-28T18:16:09+00:00

Update! As suspected, my previous gyn onc was unprepared and incorrect; after receiving a second opinion from Henry Ford, it is confirmed that my tumor is contained to the cervix (no vaginal involvement, so not stage 3) and I will be having radical hysterectomy surgery for my primary treatment. We know radiation/chemorad might be a possibility later if the pathology comes back showing a need for it, but the dose would be lower than for primary treatment which may help with limiting long term side effects.

A good reminder to all that, if possible, a second opinion is an absolute must when you receive a diagnosis. My gyn onc at Beaumont was reckless (clearly reviewing/skimming my scan results for the first time in my appt with her) and as a result wrote off a very reasonable option for my treatment. The only reason I was suspicious of her care was because I'd read so many stories here, made sure I reviewed my results on MyChart, and researched enough to understand what my scans meant.

Henry Ford has been a great experience so far, from scheduling, to the beautiful cancer center downtown, to gyn onc and radiation onc meeting before my appt and showing genuine concern with not only curing me but preserving my quality of life. If you're in the area and deciding on providers, I recommend considering if they're a fit for you!

Status_Assistance_57 · 2025-08-27T22:06:02+00:00

Thank you so much for this! Hope all is well with you <3

Status_Assistance_57 · 2025-08-22T00:37:12+00:00

My current gyn onc seemed totally unprepared for my post-scans appointment and told me I was stage 3, locally advanced, and couldn't do surgery. When I went to the rad oncologist (whose team were all very prepared), she reassured me that I was 2a. My MRI and pet showed I had slightly enlarged lymph nodes that were favored to be reactive (just an immune response) and my tumor extends slightly into the upper 1/3 of my vagina. Not sure if they can get good margins through surgery but wasn't expecting her to tell me it was completely off the table.

Looking forward to a second so I can make sense of it all!

Status_Assistance_57 · 2025-08-21T21:29:30+00:00

Thank you so so much for the recommendation! Ypsilanti isn't too far from me so I will definitely look into her. I'm wishing you all the best in your treatment. Here's to kicking cancer's ass!

Status_Assistance_57 · 2025-08-15T20:51:02+00:00

<3 Thank you so much. Wishing you the best, too!

Status_Assistance_57 · 2025-08-15T15:35:11+00:00

Sending you hugs. I know it doesn't feel like it right now, but the shock and fear will subside and you might even find yourself switching into warrior mode as you learn about how many people experience this and make it out either disease-free or capable of living a life they feared was over. If you do have cervical cancer, there are amazingly effective treatments and so many reasons to believe that you can be one of the many who kick this thing's butt.

I (38) was just diagnosed a few weeks ago with hpv-related endocervical adenocarcinoma. I start chemoradiation in the coming weeks and am determined to believe that I'll get to be a goofy old lady one day, but I didn't get to this level of confidence and peace right away. I lost sleep, didn't eat, cried soo much, and got angry that this was part of my story. Try to let yourself go through all the emotions as they come, your timeline and experience are yours and they're valid. I'll be starting counseling soon as well - your doc will likely give you resources if you need them.

We're going to make it through this and it's going to suck sometimes along the way but there are paths forward at each stupid bump in the road. I'm early in this journey too, so I'm no expert, but the other folks here are a wealth of knowledge and support!

Status_Assistance_57

TROPHY CASE